ID A0A1S3ESV8_DIPOR Unreviewed; 804 AA.
AC A0A1S3ESV8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Tudor domain-containing protein 3 {ECO:0000256|ARBA:ARBA00013421};
GN Name=Tdrd3 {ECO:0000313|RefSeq:XP_012866512.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012866512.1};
RN [1] {ECO:0000313|RefSeq:XP_012866512.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012866512.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_012866512.1; XM_013011058.1.
DR AlphaFoldDB; A0A1S3ESV8; -.
DR GeneID; 105981750; -.
DR KEGG; dord:105981750; -.
DR CTD; 81550; -.
DR InParanoid; A0A1S3ESV8; -.
DR OrthoDB; 228723at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR CDD; cd20413; Tudor_TDRD3; 1.
DR CDD; cd14282; UBA_TDRD3; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 2.40.50.770; RecQ-mediated genome instability protein Rmi1, C-terminal domain; 1.
DR InterPro; IPR042470; RMI1_N_C_sf.
DR InterPro; IPR013894; RMI1_OB.
DR InterPro; IPR002999; Tudor.
DR InterPro; IPR047379; Tudor_TDRD3.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR InterPro; IPR041915; UBA_TDRD3.
DR PANTHER; PTHR13681; SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED; 1.
DR PANTHER; PTHR13681:SF24; TUDOR DOMAIN-CONTAINING PROTEIN 3; 1.
DR Pfam; PF08585; RMI1_N_C; 1.
DR Pfam; PF00567; TUDOR; 1.
DR Pfam; PF00627; UBA; 1.
DR SMART; SM01161; DUF1767; 1.
DR SMART; SM00333; TUDOR; 1.
DR SMART; SM00165; UBA; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS50304; TUDOR; 1.
DR PROSITE; PS50030; UBA; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000081671}.
FT DOMAIN 286..326
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT DOMAIN 648..708
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT REGION 242..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 327..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 399..459
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 477..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 721..741
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..280
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..357
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 410..431
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 432..458
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 529..548
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 804 AA; 89163 MW; E61985ACD6513F0E CRC64;
MAEAPGAALS QAGWYLSEEG IEACTSSPDK INVNDIILIA LNTDLRTIGK KFLPSDINGG
KVEKLEGPCV LQIQKIRNVA APKDNEESQA APRMLRLQMT DGHTSCTAVE FSYMPKISLN
TPPGTKIKLS GIVDIKNGFL LLNDSNTTVL GGEVEHLIDK WELQRSLSKH NRSNIGTEGG
PPPFVPFGQK CISHAQVDSR ELDRRKTLQV TMPVKTTNDN DEFEKQRTAA IAEVAKSKET
KTFGGGGGGV RGNLNMGSVG NRNREVLQKE KSSKAEGKHE GVYRELVDEK ALKHITEMGF
SKEASRQALM DNGNNLEAAL NVLLNSNKQK PVVGPPPRGR GKGRGRGRSE DEDDLGNARP
SAPSTLFDFL ESKMGTLNVE EPKSQPQHLH QGQYRMSNTE QNGVKDNNQP RHFPRNDTRQ
TRNEKPPRFQ RDTQTLKSAL EVSGLSRNRG SERLNTSTGA EVWAEERIKC DRPYSRYDRT
KDTACPSTSQ HSDGAFKKRD NSMQSRPSKG PSYGEAKENP LPQESIDYNN QKRGKRENYT
GNPDHFYDRK SRTITNEAFS SVKVEKHFNV STNYQHPVRS NNFIGVPNGE TDMPLRGRRV
GPMQPAGPAA VEPYDDKIFY NSGPKRRSGP IKPEKVLESS IPMEYAKVWK PGDECFALYW
EDNKFYRAEV EALHSSGMTA VVKFIDYGNY EEVLLSNIKP IQTEAWCLSL AESSIQKGEE
VLQHSRGAGN AQDESEDLGS SPGSATYYLC DFGKKKAPMT KLLSSEEVVM ASQEDPLGQL
SSFTNLPGLG TDMKRFFVKK GVVD
//
