UniProt: A0A1S3EY38

Database: UniProt
Entry: A0A1S3EY38_DIPOR

LinkDB:  A0A1S3EY38_DIPOR 
Original site:  A0A1S3EY38_DIPOR

All links

Ontology (10)   
   GO (10)   
Gene (2)   
   KEGG GENES (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
Protein domain (35)   
   InterPro (21)   
   Pfam (11)   
   PROSITE (2)   
   SMART (1)   
All databases (48)   

Download RDF

ID   A0A1S3EY38_DIPOR        Unreviewed;      3944 AA.
AC   A0A1S3EY38;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Dynein heavy chain 7, axonemal {ECO:0000313|RefSeq:XP_012868820.1};
GN   Name=Dnah7 {ECO:0000313|RefSeq:XP_012868820.1};
OS   Dipodomys ordii (Ord's kangaroo rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC   Dipodomyinae; Dipodomys.
OX   NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012868820.1};
RN   [1] {ECO:0000313|RefSeq:XP_012868820.1}
RP   IDENTIFICATION.
RC   TISSUE=Kidney {ECO:0000313|RefSeq:XP_012868820.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell projection, cilium, flagellum
CC       {ECO:0000256|ARBA:ARBA00004230}. Cytoplasm, cytoskeleton, cilium
CC       axoneme {ECO:0000256|ARBA:ARBA00004430}.
CC   -!- SIMILARITY: Belongs to the dynein heavy chain family.
CC       {ECO:0000256|ARBA:ARBA00008887}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_012868820.1; XM_013013366.1.
DR   STRING; 10020.ENSDORP00000017042; -.
DR   GeneID; 105983455; -.
DR   KEGG; dord:105983455; -.
DR   CTD; 56171; -.
DR   InParanoid; A0A1S3EY38; -.
DR   OrthoDB; 166463at2759; -.
DR   Proteomes; UP000081671; Unplaced.
DR   GO; GO:0005930; C:axoneme; IEA:UniProt.
DR   GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR   GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR   GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   Gene3D; 1.10.287.2620; -; 1.
DR   Gene3D; 1.10.472.130; -; 1.
DR   Gene3D; 1.10.8.1220; -; 1.
DR   Gene3D; 1.10.8.710; -; 1.
DR   Gene3D; 1.20.1270.280; -; 1.
DR   Gene3D; 1.20.58.1120; -; 1.
DR   Gene3D; 1.20.920.20; -; 1.
DR   Gene3D; 1.20.920.30; -; 1.
DR   Gene3D; 3.10.490.20; -; 1.
DR   Gene3D; 6.10.140.1060; -; 1.
DR   Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR   Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR   Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR035699; AAA_6.
DR   InterPro; IPR035706; AAA_9.
DR   InterPro; IPR041658; AAA_lid_11.
DR   InterPro; IPR042219; AAA_lid_11_sf.
DR   InterPro; IPR026983; DHC_fam.
DR   InterPro; IPR041589; DNAH3_AAA_lid_1.
DR   InterPro; IPR042222; Dynein_2_N.
DR   InterPro; IPR043157; Dynein_AAA1S.
DR   InterPro; IPR041466; Dynein_AAA5_ext.
DR   InterPro; IPR041228; Dynein_C.
DR   InterPro; IPR043160; Dynein_C_barrel.
DR   InterPro; IPR024743; Dynein_HC_stalk.
DR   InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR   InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR   InterPro; IPR013602; Dynein_heavy_linker.
DR   InterPro; IPR042228; Dynein_linker_3.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR46961:SF18; DYNEIN AXONEMAL HEAVY CHAIN 1; 1.
DR   PANTHER; PTHR46961; DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN; 1.
DR   Pfam; PF12774; AAA_6; 1.
DR   Pfam; PF12775; AAA_7; 1.
DR   Pfam; PF12780; AAA_8; 1.
DR   Pfam; PF12781; AAA_9; 1.
DR   Pfam; PF17857; AAA_lid_1; 1.
DR   Pfam; PF18198; AAA_lid_11; 1.
DR   Pfam; PF08393; DHC_N2; 1.
DR   Pfam; PF17852; Dynein_AAA_lid; 1.
DR   Pfam; PF18199; Dynein_C; 1.
DR   Pfam; PF03028; Dynein_heavy; 1.
DR   Pfam; PF12777; MT; 1.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF47473; EF-hand; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
DR   PROSITE; PS00018; EF_HAND_1; 1.
DR   PROSITE; PS50222; EF_HAND_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW   Cilium {ECO:0000256|ARBA:ARBA00023069};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Dynein {ECO:0000256|ARBA:ARBA00023017};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW   Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000081671}.
FT   DOMAIN          2160..2195
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   COILED          2751..2799
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   3944 AA;  451891 MW;  763DC76A68AF6A52 CRC64;
     MQDKPASKDK SKAPAGILPQ LSTVTVHSEL ILGLEVQSPV PTTTALISES ALQQQDADLD
     LADLEENKLP KLTTSAIEKD ILRYYYYIHH GIDTDHVAPM EDSWLEHVLN LVPQHLKVLT
     DSIIVLSDEM RDDYLLSVKK SIVDFVLKDP REKEDDRKTV ELPPHRAEME VLPKPWRKSF
     LSACSYIREH LNAMNPTMLA VLDLWHSTFK KLRLIDVEDF HNRQDALELS VFQNLVMRHM
     ESAKETLLKT WFPEVQNIYY QGNKKRQLPT GDNSSKLESF FNCAATLMTL QLQELTLVSM
     QDFTDLIAQP PESVRAFEHP GFIMRLVLDV DTIKFEPDFN DYIDILVNVY DVMMKAVSFV
     PRVETKLYSK WESRSKPTTL KPIILDDIVK AHKEKIREVV MKESVAPMEH LKLYDKYDFL
     ITKQAEKDVD AFLAEDHSYE TIIEEIRKYQ RLSEEIRYTS RKTVRLGMFE MHCEELIRAL
     VKRADIICGK LIAKMFRNHQ DVNTRLCEEF ERIAEKALST PPNTAELMEM KAYIQKVEAT
     DMIELGQRLV DSKNCLSFLI ECVNFSPADI RLNNSVFQWY ARMGEIFEEH RKIIKEKTEQ
     YQEGLKLRCD RFVEELESYA KQAEEFYTFG DIQDVPRYLK KAQTLNGKLD IAADKIEQFN
     TEEEAYGWVP SVYPQRKKIQ DGLNPYLRLY ETIVEFSTKH RAWTEGPYHK VNPDQVETDV
     GNYWRGLYKL EKIFHDSPNA LAMTKKVRAK VEEFKQYIPL IQVICNPGLR PRHWEAMSNI
     VGYPLQPADD ATVFSFLDMH LEPYLDKFEG ISEAASKEYS LEKSLEKMVT EWDSMEFVIH
     PYRESGTFIL SSVDEIQMLL DDHIIKTQTM RGSPFIKPYE KQMREWEAKL LLLQEILDEW
     LKVQATWLYL EPIFSSPDIM SQMPEEGRRF TTVDKTWRDI MKNVAQDKHV LSVVTIEKML
     ERMKKSNELL ELILKGLNEY LEKKRLFFPR FFFLSNDELL EILSETKDPT RVQPHLKKCF
     EGIARVEFTE TLEITHMKSS EGEVVELIET ISTAKARGQV EKWLVELERV MIRSIHKVIG
     DAILAYTKVE RIKWVRDWPG QTVLCVSQTF WTKEVQTAIP MGLTTLQKYL EKCNRQIDDI
     VTLVRGKLSK QNRVTLGALV VLDVHARDVL AALVNKSVMD DNDFEWLSQL RYYWQENQLQ
     TKMINAGLRY GYEYLGNSPR LVITPLTDRC YRTLFGALHL HLGGAPEGPA GTGKTETTKD
     LAKAVAKQCV VFNCSDGLDY LALGKFFKGL LSCGAWACFD EFNRIDLEVL SVVAQQILTI
     QRGINAGTDI LVFEGTELKL DPTCAVFITM NPGYAGRSEL PDNLKALFRT VAMMVPDYAM
     IAEIVLYSCG FVTARPLSVK IVATYRLCSE QLSSQHHYDY GMRAVKSVLT AAGNLKLKYP
     NENEEILLFR SIIDVNLPKF LSHDLPLFEG ITSDLFPGVK LPKPDYNDLL AAIKDNCVAM
     NLQMTKFFSD KILQIYEMMI VRHGFMIVGE PFGGKTSAYR VLAGALNDIC EKGLMEENKV
     QITVLNPKSV TMGQLYGQFD LVSHEWSDGV LAVSFRAFAS SMTPDRKWLI FDGPVDAVWI
     ENMNTVLDDN KKLCLMSGEI IQMSPQMNLI FEPMDLEVAS PATVSRCGMI YMEPHMLGWR
     PLMLSWINIL PPSVNAIQKE FIIGLFDRMV PLSVEFIRRH TKELSPTSDT NLVRSLMNLI
     DCFIDDFADE AKQKERNDRE SFSLLEGIFL FSLIWSVGAT CTAEDRVKFS KILRELMEGP
     MSDLTRNRFK LLSGTENTST KKLTVPFPDK GTIYDYQFIS EGLGKWEPWI KKLEEAPPIP
     KDVQFNEIIV PTLDTIRYSV LMNLLTTHQK PSIFVGPTGT GKSVYIINFL LNQINKEIYK
     PLIVNFSAQT TAAQTQNIIM SKLDKRRKGV FGPPLGKRMV VFVDDVNMPA REVYGAQPPI
     ELLRQWLDHW NWYDLKDCSM IKLVDIQIMC AMGPPGGGRN PVTPRYMRHF NIITINDFSD
     KSMFTIFSRI LTWHLKICYK FPEDFLDLTT QIVNGTMTLY KDAMKNLLPT PAKSHYLFNL
     RDFSRVIQGV CLSRPETAET KEVIKRLWVH EVLRVYYDRL LDNADRSWLI QYIQDVLKNY
     MYEDFHELFK SLDFDGDGVV EEDDLRSLMF CDFHDPKRED TSYREVKNVD ALRVIAESHL
     EEYNNMSKKP MNLVLFRFAI EHISRISRIL KQPRSHALLV GVGGSGRQSV TRLAAHMADY
     SVFQVEISKG YGSNEWREDL KVILRKCAES DMHGIFLFTD TQIKRESFLE DINNLLNAGE
     VPNLFALDEK QEICEKMRQL DRQRDKTKQT DGSPIALFNM FIERCRNQLH VVLAMSPIGD
     AFRNRLRKFP ALVNCCTIDW FQSWPEDALE AVASRFLEEI EMSEEIREGC IDMCKSFHTS
     TIILSASFHS ELQRYNYVTP TSYLELISTF KVLLEKKRSE VMKMKKRYEV GLDKLDSASS
     QVATMQLELE ALHPQLKVAS KEVDEMMIII EKESVEVAKT EKVVKADETV ANEQAMAAKA
     IKDECDADLA GALPILESAL SALDTLTAQD ITVVKSMKSP PAGVKLVMEA ICILKGIKAD
     KIPDPTGSGK KTEDFWGPAK RLLGDIRFLQ SLHEYDKDNI PPAYMNIIRK NYIPNPDFVP
     EKIRNASTAA EGLCKWVIAM DSYDKVAKIV APKKIKLAAA EGELKIAMDG LRKKQAALKE
     VQDKLAKLQD TLELNKQKKA DLENQVDLCS KKLERAEQLI GGLGGEKTRW SRSALELGQL
     YINLTGDILI SSGVVAYLGA FTSSYRQNQT KEWTNLCKGR DIPCSDDYSL MGTLGEAVTI
     RAWNIAGLPS DSFSIDNGII IMNARRWPLM IDPQGQANKW VKNMEKTNSL QLIKFSDPDY
     VRTLENCIQF GTPVLLENVG EELDPILEPL LLKQTFKHSG SLCIRLGDST IEYSPDFRFY
     ITTKLRNPHY LPETSVKVTL LNFMITPEGM QDQLLGIVVA RERPDLEEEK QALILQGAEN
     KRQLKEIEDK ILEVLSSSEG NILEDETALK ILSSSKALAN EISQKQEVAE ETEKKIDSTR
     MGYRPIAIHS SILFFSIADL ANIEPMYQYS LVWFINLFIL SIENSEKSEV LQNRLQILKD
     HFTYSLYVNI CRSLFEKDKL LFSFCLTVNL LIHDNAINKT EWRFLLTGGI GLDNPFTNPC
     AWLPQKSWDE ICRLDDLSSF KNIRKDFAQL KDEWKVVYDS LDPHHELFPE EWEDKMDEFQ
     RMLIIRCLRP DKVIPMLQEF ITNKLGRAFI EPPPFDLSKA FGDSNCCAPL IFILSPGADP
     MAALLKFSDD QGYGGSKLSS LSLGQGQGPI AMKMVEKAVK EGTWVVLQNC HLATSWMPTL
     EKVCEELSPE TTHPDFRLWL TSYPSPNFPV SVLQNGVKMT NEAPKGLRAN IIRSYLMDPI
     SDPEFFGSCK KPEEFKKLLY GLCFFHALVQ ERRKFGPLGW NIPYEFNETD LRISVQQLHM
     FLNQYEELPY DALRYMTGEC NYGGRVTDDW DRRTLRSILN KFFNSELVQN PEYKFDSSGI
     YFAPPSGDHK SYIEYTKTLP LTPLPEIFGM NANADITKDQ SETQLLFDNI LLTQSRASGA
     GAKSSDEVVN EVASDILGKL PNNFDVEAAM RRYPTTYTQS MNTVLVQEMG RFNKLLKTIR
     ESCINIQKAI KGLVVMSSEL EEVVSSILNV KIPGMWMGKS YPSLKPLGSY VNDFLARLKF
     LQQWYETGPP PVFWLSGFFF TQAFLTGAQQ NFARKYTIPI DLLGFDYEVM EDKEYKTPPE
     DGVYIHGLFL DGASWNRKTK KLAESYPKVL YDTVPVMWLK PCKRTDIEKR PSYIAPLYKT
     SERRGTLSTT GHSTNFVIAM ILPSDEPKEH WIGRGVALLC QLNS
//

DBGET integrated database retrieval system