ID   A0A1S3EYK5_DIPOR        Unreviewed;       819 AA.
AC   A0A1S3EYK5;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=Dynein regulatory complex protein 1 {ECO:0000256|ARBA:ARBA00013815};
DE   AltName: Full=Coiled-coil domain-containing protein 164 {ECO:0000256|ARBA:ARBA00031554};
GN   Name=Drc1 {ECO:0000313|RefSeq:XP_012868990.1};
OS   Dipodomys ordii (Ord's kangaroo rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC   Dipodomyinae; Dipodomys.
OX   NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012868990.1};
RN   [1] {ECO:0000313|RefSeq:XP_012868990.1}
RP   IDENTIFICATION.
RC   TISSUE=Kidney {ECO:0000313|RefSeq:XP_012868990.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC       {ECO:0000256|ARBA:ARBA00004430}. Cytoplasm, cytoskeleton, flagellum
CC       axoneme {ECO:0000256|ARBA:ARBA00004611}.
CC   -!- SIMILARITY: Belongs to the DRC1 family.
CC       {ECO:0000256|ARBA:ARBA00009688}.
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DR   RefSeq; XP_012868990.1; XM_013013536.1.
DR   AlphaFoldDB; A0A1S3EYK5; -.
DR   STRING; 10020.ENSDORP00000012333; -.
DR   GeneID; 105983589; -.
DR   KEGG; dord:105983589; -.
DR   CTD; 92749; -.
DR   InParanoid; A0A1S3EYK5; -.
DR   OrthoDB; 5476746at2759; -.
DR   Proteomes; UP000081671; Unplaced.
DR   GO; GO:0005858; C:axonemal dynein complex; IEA:InterPro.
DR   GO; GO:0031514; C:motile cilium; IEA:UniProtKB-KW.
DR   GO; GO:0070286; P:axonemal dynein complex assembly; IEA:InterPro.
DR   InterPro; IPR039505; DRC1/2_N.
DR   InterPro; IPR039750; DRC1/DRC2.
DR   InterPro; IPR029440; DRC1_C.
DR   PANTHER; PTHR21625:SF1; DYNEIN REGULATORY COMPLEX PROTEIN 1; 1.
DR   PANTHER; PTHR21625; NYD-SP28 PROTEIN; 1.
DR   Pfam; PF14772; NYD-SP28; 1.
DR   Pfam; PF14775; NYD-SP28_assoc; 1.
PE   3: Inferred from homology;
KW   Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW   Cilium {ECO:0000256|ARBA:ARBA00023069};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Flagellum {ECO:0000256|ARBA:ARBA00022846};
KW   Reference proteome {ECO:0000313|Proteomes:UP000081671}.
FT   DOMAIN          100..201
FT                   /note="Dynein regulatory complex protein 1/2 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14772"
FT   DOMAIN          739..798
FT                   /note="Dynein regulatory complex protein 1 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14775"
FT   REGION          15..34
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          642..696
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          104..141
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          169..214
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          282..387
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          766..800
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        20..34
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        648..674
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   819 AA;  95432 MW;  16810E6C16E036FE CRC64;
     MNPQTPIPIE ALVEQNAEEA APNQGPSILS DNPQERIQAR RLRIAARLEA RRREALGEYL
     DGKKESEEDQ SKSYKQKEES RLKLAKLLLC GTELVTNIQV ATDIREIHRR VEEEELKRQR
     IEKLENEVKT SQDKFDEITA KWEEGKRKQI PQELWEMLNH QQQHCARLIE DKNKLISELQ
     QELKVKDDQY VKDLKKQSDD IALLLERMEE QVKNVMKTFR QELSHIEKAF EVERQELLTS
     NKKKWERALQ THNAKELEYL INRMKKVEDY EKQLNKQRVW DCEEYNSIKI KLEQDVQILE
     QQLQQMKATY QLNQEKLEYN FQVLKKRDEE STVIKSQQKR KINRLHDILN NLRSKYAKQI
     KMFHEENQNL TSDYQRLVIQ FKDLQKAMRH FALIDEEKFR EVWLMNEEEV KAIVAKAFNV
     DMVISTQHLG LPWTAPDYWF LKNVGPLSQQ QQKSATQIVE EVLMQTEEEG NEEAVPGMET
     YMDLPKQISP QTTRKILTLL CDESGFLIES KLLSLLLPLE RSECYLLRLD AIFSALGIES
     EDDLYKLVNF FLKYRAHQLS PSQGSLGDQT KMDRSSFLSA LERPSLMSAL ERSSLMTIER
     SSLMTTERTS LMLALERSSL ARSSLTSAWS KKKFLPKLKL ELPELESSDQ EPSGQESSGQ
     ESSGQESSGQ GPSAWEASAP AEGEDQDKER QTSISSELIH PNDVLKILEA FVMGLNKPRD
     LATTPRKRKG ARDDSKDSQY WEALTTVIPP VKQNLWDALY EALEKYHLLL TERTRLLREN
     NNLEKQNADL QAMLQQYLNS KINSELHIPP TQVFQMPTK
//