ID   A0A1S3F226_DIPOR        Unreviewed;       418 AA.
AC   A0A1S3F226;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Clusterin {ECO:0000256|RuleBase:RU000629};
GN   Name=Clul1 {ECO:0000313|RefSeq:XP_012870280.1};
OS   Dipodomys ordii (Ord's kangaroo rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC   Dipodomyinae; Dipodomys.
OX   NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012870280.1};
RN   [1] {ECO:0000313|RefSeq:XP_012870280.1}
RP   IDENTIFICATION.
RC   TISSUE=Kidney {ECO:0000313|RefSeq:XP_012870280.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the clusterin family.
CC       {ECO:0000256|ARBA:ARBA00010069, ECO:0000256|RuleBase:RU000629}.
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DR   RefSeq; XP_012870280.1; XM_013014826.1.
DR   AlphaFoldDB; A0A1S3F226; -.
DR   GeneID; 105984600; -.
DR   KEGG; dord:105984600; -.
DR   CTD; 27098; -.
DR   InParanoid; A0A1S3F226; -.
DR   OrthoDB; 5320180at2759; -.
DR   Proteomes; UP000081671; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR000753; Clusterin-like.
DR   InterPro; IPR016015; Clusterin_C.
DR   InterPro; IPR016014; Clusterin_N.
DR   PANTHER; PTHR10970; CLUSTERIN; 1.
DR   PANTHER; PTHR10970:SF2; CLUSTERIN-LIKE PROTEIN 1; 1.
DR   Pfam; PF01093; Clusterin; 2.
DR   SMART; SM00035; CLa; 1.
DR   SMART; SM00030; CLb; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Reference proteome {ECO:0000313|Proteomes:UP000081671};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..418
FT                   /note="Clusterin"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5010288075"
FT   DOMAIN          26..236
FT                   /note="Clusterin N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00030"
FT   DOMAIN          237..412
FT                   /note="Clusterin C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00035"
FT   COILED          73..111
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   418 AA;  48415 MW;  C1963A55E4645A11 CRC64;
     MKPLLLVFAA CLLCWKDCPC APTWKDRTAL GGNLKGLLEE GETEAGGELK KALMGMKQMR
     IVMGRREEEH GRLMETLKKC KEEKQEALKL MNEVQEHLEE EERLCQASSA NSWDRCRYCL
     QSKYVRLYTT RKPGWSSVKS TMEQFFRKLY QFLFPLHDDQ DDLPAHGKST EEDPRVTQME
     GVFCQLTEDV RILFNRSLFV FKQMQQEFDQ AFQSYFMSDS DLMEPSFFPT FSKKPIPKAD
     LEPRWDLPNF FRLLGNLSLS VYERVSKSIK STLDAIQDSS TPHQDCPDVP DLHTELDEAL
     RLVNLSSQQY DQIVRMTQYH VQDTLHLMEK MKAQFGWVSE LASKIPGAEN ISDLTKGVLS
     DREGHSFQQA ETRVDSHILP SPNFTVKITP DTSAESSNFM DYMAAKVLEH FREHFKTW
//