ID A0A1S3F3D8_DIPOR Unreviewed; 2216 AA.
AC A0A1S3F3D8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Lipoxygenase homology domain-containing protein 1 isoform X1 {ECO:0000313|RefSeq:XP_012870302.1};
GN Name=Loxhd1 {ECO:0000313|RefSeq:XP_012870302.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012870302.1};
RN [1] {ECO:0000313|RefSeq:XP_012870302.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012870302.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00152}.
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DR RefSeq; XP_012870302.1; XM_013014848.1.
DR GeneID; 105984610; -.
DR KEGG; dord:105984610; -.
DR CTD; 125336; -.
DR InParanoid; A0A1S3F3D8; -.
DR OrthoDB; 5399012at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR CDD; cd01756; PLAT_repeat; 13.
DR Gene3D; 2.40.180.10; Catalase core domain; 9.
DR Gene3D; 2.60.60.20; PLAT/LH2 domain; 7.
DR InterPro; IPR001024; PLAT/LH2_dom.
DR InterPro; IPR036392; PLAT/LH2_dom_sf.
DR PANTHER; PTHR45901:SF6; LIPOXYGENASE HOMOLOGY DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR45901; PROTEIN CBG12474; 1.
DR Pfam; PF01477; PLAT; 15.
DR SMART; SM00308; LH2; 12.
DR SUPFAM; SSF49723; Lipase/lipooxygenase domain (PLAT/LH2 domain); 16.
DR PROSITE; PS50095; PLAT; 15.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000081671}.
FT DOMAIN 43..160
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 172..287
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 296..412
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 425..540
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 553..673
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 684..803
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 814..929
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 1026..1144
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 1180..1298
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 1311..1436
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 1465..1583
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 1701..1816
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 1828..1946
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 1959..2080
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 2097..2213
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT REGION 935..985
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1151..1171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 951..985
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2216 AA; 253530 MW; 66C89776B0072F9F CRC64;
MMPQKKKRRK KDIDFLRVYE EELLNYVSED DEDELEHEYY KAKVYEVVTA TGDVRGAGTD
ANVFITIFGE NGLSPKLHLT SKSESAFEKA NVDVFRIRTN NVGLIYKIRI EHDNTGLNAS
WYLDRVIVTD MKRPHLRYYF NCNNWLSKEE GDRQWCRDLL ASFNPMDTPR GNKYEIKVYT
GDVIGAGTDA DVVINIFGEY GDTGERRLES GKDNFERGAE DKFLLDAPDL GQLMKINVGH
NNKGSSAGWF LSKIVIEDIG NKRKYDFPLN RWLALDEDDG KIQRDILVGG AETTAITYIV
TIFTGDIRGA GTKSKIYLVM YGARGNKNSG KIFLEGGVFD RGRTDIFQIE RAVLLSPLSR
VSIGHGNVGV NRGWYCEKVV ILCPFTGIQQ TFPCSNWLDE KKADGLIERQ LYEMVSLRKK
RLKKFAWSLW VWTTDLKKAG TNSPIFIQIY GQKGRTDEIL LNPNNKWFKP GTVEKFRIEL
PDLGRFYKIR AWHDRRNPGS GWHLERMTLM NILNKDKYNF NCNRWLDANE DDNEIVREMT
AEGPTVRRIM GMARYRVTVC TGELEGAGTD ANVYLCLYGD VGDTGERLLY NCRNNTELFE
KGNADEFTIE SVTMRKVRRV RVRHDGKGSS SSWYLDRVLV REEGQPESDN VEFPCLRWLD
KDQDDGQLVR ELLPSDSSAT LKNFRYHISV KTGDISGAST DSKVYIKLYG EKSDTIKQVL
LVSDNNLKDY FERGRVDEFT LETLNIGTIN RLVIGHDSTG MHSSWFLGSV QVRVPRQGKQ
YTFPANRWLD KNKADGRLEV ELYPSEVVEI QKLVHYEVEI WTGDIGGAGT TARVFMQIYG
EEGKTEVLFL SSRSKVFDRA SKDIFQLEAA DVGEIYKIRL GHTGEGFGPS WFVDTVWLRH
LVVREEDLTP EEEARKKKEK DKLRQLLKKE RLKAKLQRKK KKKKKGSDEE EESGEEEESS
SEESSSEEEE EEESEEEEEE EEYGPGMQAV IEQHKFEAHR WLARGKEDDE LVVELVPTGQ
SGPEPNTYEV QVITGNVPKA GTDANVYLTI YGEEYGDTGE RSLKKSDKSN KFEQGQTDTF
TLYAIDLGPL TKIRIRHDNT GSRPGWFLDR IDITDMNNEI TYYFPCQRWL AVEEDDGQLS
RELLPVDESY VLPSEDDEGG GHGDNNPLDN MALEQKDKST TFSVTIKTGD KKNAGTDANV
FITLFGTQDD TGITLLKSSK TNTDKFERDS IEIFTVETLD LGDLWRVRIG HDNTGKAPGW
FVDWVEVDAP SLGKRMTFPC GRWLAKNEDD GMIVRDLFHA ELQTRLYTPF VPYEITLYTS
DVFAAGTDAN IFIVIYGCDA VCTTQKFLCT NKREQKMFFE RKSASRFIVE LEDVGEIIEK
IRIGHDNTGV NPGWHCSHVD IRRLLPDKDG TETLTFPCDR WLATSEDDKK TIRELVPYDI
FTEKYMKDGS LRQVYKEVEE PLDIVLYSVQ IFTGNVPGAG TDARVYITIY GDLGDTGERY
LGKSENRINK FEKGTADTFI IEAADLGVIY KIKLRHDNTK WYADWYVEKV EIWNDTNEDE
FLFLCGRWLS LKKEDGRLER LFYEKEYTGD RSSNCSSPAD FWEIALSSKM ADVDIATVTG
PMVDYVQEGP VIPYYVSVTT GKHKDAATDS RAFILLIGED DERSNRIWLD YPQGKKGFRC
GSVEEFYVGG LDVGIIKKIE VLYEMTVWTG DVVGGGTDSN IFMTLYGING STEEVQLDKK
KARFEREQND TFIMEILDIA PFTKMRIRID GLGSRPEWFL EKVLLKNMNT GDLTMFYYRD
WLSQRKGKKT LVCEMCAVID GEEMMEWTSY TVTVKTSDIL GAGTDANVSI IIFGENGDSG
TLALKQSANW NKFERNNTDT FNFSDMLSLG HLCKLRVWHD NKGIFPGWHL SYVDVKDNSR
DETFRFQCDC WLSKSEGDRQ TVRDFACANN AIREELEETT YEIVIETGNG GETRENVWLI
LEGRKNRSKE FLVENSSRQR AFRKGATDTF EFDSIFLGDI ASLCVGHLAR EDRFIPKREL
AWHVKTITIT EMEYSNVYFF NCDCLIPLKR KRKYFKVFEV TKTTESFASR IQSLVPVKYE
IIVTTGYELG AGTDANVFVT IFGSNGDTGK RELKQKMRNL FERGSTDRFF LETLELGELR
KVRLEHDSSG YYSGWLVDKV EVTNTSTGVA TIFTCGRWLD KSRGDGLTWR DLFPSV
//
