ID   A0A1S3F3U4_DIPOR        Unreviewed;       725 AA.
AC   A0A1S3F3U4;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Semaphorin-6C {ECO:0000313|RefSeq:XP_012870462.1};
GN   Name=Sema6c {ECO:0000313|RefSeq:XP_012870462.1};
OS   Dipodomys ordii (Ord's kangaroo rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC   Dipodomyinae; Dipodomys.
OX   NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012870462.1};
RN   [1] {ECO:0000313|RefSeq:XP_012870462.1}
RP   IDENTIFICATION.
RC   TISSUE=Kidney {ECO:0000313|RefSeq:XP_012870462.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR   RefSeq; XP_012870462.1; XM_013015008.1.
DR   AlphaFoldDB; A0A1S3F3U4; -.
DR   STRING; 10020.ENSDORP00000025587; -.
DR   GeneID; 105984732; -.
DR   KEGG; dord:105984732; -.
DR   CTD; 10500; -.
DR   InParanoid; A0A1S3F3U4; -.
DR   OrthoDB; 5399685at2759; -.
DR   Proteomes; UP000081671; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   CDD; cd11268; Sema_6C; 1.
DR   Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR002165; Plexin_repeat.
DR   InterPro; IPR001627; Semap_dom.
DR   InterPro; IPR036352; Semap_dom_sf.
DR   InterPro; IPR027231; Semaphorin.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR11036; SEMAPHORIN; 1.
DR   PANTHER; PTHR11036:SF11; SEMAPHORIN-6C; 1.
DR   Pfam; PF01437; PSI; 1.
DR   Pfam; PF01403; Sema; 1.
DR   SMART; SM00630; Sema; 1.
DR   SUPFAM; SSF103575; Plexin repeat; 1.
DR   SUPFAM; SSF101912; Sema domain; 1.
DR   PROSITE; PS51004; SEMA; 1.
PE   4: Predicted;
KW   Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW   Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW   Reference proteome {ECO:0000313|Proteomes:UP000081671};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           27..725
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5010189712"
FT   TRANSMEM        607..631
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          32..518
FT                   /note="Sema"
FT                   /evidence="ECO:0000259|PROSITE:PS51004"
FT   REGION          558..589
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          695..725
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   725 AA;  78478 MW;  F7E5D202CAF85DBC CRC64;
     MPRAPYLMPL LLLLLLLLLS LPHTQAAFPQ DPLPLLTSDL QGTSPLTWFR GLEDDAVAAE
     LGLDFQRFLT LNRTLLVAAR DHVFSFDLQA QEEGEGLVPN KYLTWRSQDM ENCAVRGKLT
     DECYNYIRVL VPWDSQTLLA CGTNSFSPMC RSYGITSLQQ EGEELSGQAR CPFDATQSNV
     AIFAEGSLYS ATAADFQASD AVVYRSLGPQ PPLRSAKYDS KWLREPHFVH ALEHGEHVYF
     FFREVSVEDA RLGRVQFSRV ARVCKRDMGG SPRALDRHWT SFLKLRLNCS VPGDSTFYFD
     VLQALTGPVN LHGRSALFGV FTTQTNSIPG SAVCAFYLDD VERGFEGKFK EQRSLDGAWT
     PVSEDRVPSP RPGSCAGVGG AALFSSSQDL PDDVLTFIKA HPLLDPAVPP ATHQPLLTLS
     NRALLTQVAV DGMAGPHSNT TVLFLGSNDG TVLKVLPPGG QSGEPEPILL EEIDAYSPSR
     CSGKRAAHTA RRIIGLELDT EGHRLFVAFS GCIVYLPLSR CARHGACQRS CLASRDPYCG
     WHSSRGCVDI RGPGGPDVAL AGNHEPTEHG DCRDGATGSQ SGPGDSAYGV RRDLLPASAS
     RSVPIPLLLA SVAAAFALGA SVSGLLVSCV CRRTHHRRNK DVESPVLPRP LSLRSLARLH
     GAGLEPPPPS KDAEYSGGPG RHLLYLGRAE GYRGRAPKRV DVDKSPLSPK SPLVGAAPQG
     SHFNF
//