ID A0A1S3F8Q4_DIPOR Unreviewed; 207 AA.
AC A0A1S3F8Q4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=T-cell leukemia homeobox protein 1 {ECO:0000313|RefSeq:XP_012873043.1};
GN Name=Tlx1 {ECO:0000313|RefSeq:XP_012873043.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012873043.1};
RN [1] {ECO:0000313|RefSeq:XP_012873043.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012873043.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
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DR RefSeq; XP_012873043.1; XM_013017589.1.
DR AlphaFoldDB; A0A1S3F8Q4; -.
DR STRING; 10020.ENSDORP00000022773; -.
DR GeneID; 105986592; -.
DR KEGG; dord:105986592; -.
DR CTD; 3195; -.
DR InParanoid; A0A1S3F8Q4; -.
DR OrthoDB; 380905at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR020479; Homeobox_metazoa.
DR InterPro; IPR042247; TLX1/2/3.
DR PANTHER; PTHR45921; IP01054P; 1.
DR PANTHER; PTHR45921:SF2; T-CELL LEUKEMIA HOMEOBOX PROTEIN 1; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00024; HOMEOBOX.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000081671}.
FT DOMAIN 76..136
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 78..137
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 62..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|RefSeq:XP_012873043.1"
SQ SEQUENCE 207 AA; 23231 MW; 48BFE21562FFA3A8 CRC64;
GALSAAGVIR VPAHRPLAGA VAHPQPLATG LPTVPSVPAV PGVNNLTGLT FPWMESNRRY
TKDRFTGHPY QNRTPPKKKK PRTSFTRLQI CELEKRFHRQ KYLASAERAA LAKALKMTDA
QVKTWFQNRR TKWRRQTAEE REAERQQANR ILLQLQQEAF QKSLAQPLPA DPLCVHNSSL
FALQNLQPWS DDSTKITSVT SVASACE
//
