ID A0A1S3F962_DIPOR Unreviewed; 323 AA.
AC A0A1S3F962;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Calcium homeostasis modulator protein 2 {ECO:0000313|RefSeq:XP_012873188.1};
GN Name=Calhm2 {ECO:0000313|RefSeq:XP_012873188.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012873188.1};
RN [1] {ECO:0000313|RefSeq:XP_012873188.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012873188.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CALHM family.
CC {ECO:0000256|ARBA:ARBA00008497}.
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DR RefSeq; XP_012873188.1; XM_013017734.1.
DR AlphaFoldDB; A0A1S3F962; -.
DR STRING; 10020.ENSDORP00000009798; -.
DR GeneID; 105986700; -.
DR KEGG; dord:105986700; -.
DR CTD; 51063; -.
DR InParanoid; A0A1S3F962; -.
DR OMA; FAFHCPC; -.
DR OrthoDB; 2899675at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR InterPro; IPR029569; CALHM.
DR PANTHER; PTHR32261; CALCIUM HOMEOSTASIS MODULATOR PROTEIN; 1.
DR PANTHER; PTHR32261:SF3; CALCIUM HOMEOSTASIS MODULATOR PROTEIN 2; 1.
DR Pfam; PF14798; Ca_hom_mod; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000081671};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 21..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 54..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 323 AA; 35806 MW; F4FD274C8E0C95B7 CRC64;
MAALIAENFR FLSLFFKSKD VMIFNGLVAL GTVGSQELFS VVAFHCPCSP ARNYLYGLTA
IGVPALALFL IGVILNNHTW NLVAECQYRR AKNCSAAPNF LLLSSILGRA AVAPVTWSVI
SLLRGEAYVC ALSEFVDPSS LTAGEESFPP GHATEILARF PCGEGPDNLS GFREEVSRRL
KYESQLFGWL LIGVVAILVF LTKCLKHYCS PLSYRQEAYW AQYRTNEDQL FHRTAEVHSK
VLAANNVRRF FGFVALNKDD EELIAKFPVE GTQPRPQWNA ITGVYLYREN QGLPLYSRLH
KWAQGLAGNG TAPDSVEMAL LAS
//
