ID A0A1S3FAF9_DIPOR Unreviewed; 493 AA.
AC A0A1S3FAF9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Rho GTPase-activating protein 19 {ECO:0000313|RefSeq:XP_012873250.1};
GN Name=Arhgap19 {ECO:0000313|RefSeq:XP_012873250.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012873250.1};
RN [1] {ECO:0000313|RefSeq:XP_012873250.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012873250.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_012873250.1; XM_013017796.1.
DR AlphaFoldDB; A0A1S3FAF9; -.
DR STRING; 10020.ENSDORP00000011830; -.
DR GeneID; 105986729; -.
DR KEGG; dord:105986729; -.
DR CTD; 84986; -.
DR InParanoid; A0A1S3FAF9; -.
DR OMA; CQSPANQ; -.
DR OrthoDB; 2915239at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd04392; RhoGAP_ARHGAP19; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR047941; ARHGAP19_RhoGAP.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR14963; RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED; 1.
DR PANTHER; PTHR14963:SF7; RHO GTPASE-ACTIVATING PROTEIN 19; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000081671}.
FT DOMAIN 115..308
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 399..493
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..475
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 493 AA; 55927 MW; 26886D55E8D2C74F CRC64;
MAAEALGEGE VPARDSSRSD AICSFVICNN SSLRGQPIIF NPDFFVEKLR HEKPEVFTEL
VVSNITRLID LPGTELAQLM GEVDLKLPGG AGPATGFFRS LMTLKRKEKG VVFGSPLTEE
GIAQIYQLIE YLHKNLRVEG LFRVPGNSVR QQILRDALNN GTDIDLESGE FHSNDVATLL
KIFLGELPEP LLTHKHFNAH LKIADLMQFD DKGNKTNVPD KERQIEALQL LFLILPPPNR
NLLKLLLDLL YQTAKKQDKN KMSAYNLALM FAPHVLWPKN VTANDLQENI TKLNNGMAFM
IKHSQKLFKA PAYIRECARL HYLSSRNQVS KDDLDLTASC HAKSFQLVKP KKWNQTDSSS
QQEETQQRTE EALRELFQHV HNMPESAKKK QLIRQFHKQS LTQTPGREPS TPRVQKRARS
RSFSGLIKRK VLGSQIMTEK RNKSPTRESM AMSELKSTSK ENMNLSYSGS PAVMTPTRLK
WSEGKKERRK GFL
//
