ID   A0A1S3FB67_DIPOR        Unreviewed;       745 AA.
AC   A0A1S3FB67;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=Transcription factor RFX3 {ECO:0000256|ARBA:ARBA00040859};
DE   AltName: Full=Regulatory factor X 3 {ECO:0000256|ARBA:ARBA00042137};
GN   Name=Rfx3 {ECO:0000313|RefSeq:XP_012873883.1};
OS   Dipodomys ordii (Ord's kangaroo rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC   Dipodomyinae; Dipodomys.
OX   NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012873883.1};
RN   [1] {ECO:0000313|RefSeq:XP_012873883.1}
RP   IDENTIFICATION.
RC   TISSUE=Kidney {ECO:0000313|RefSeq:XP_012873883.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   RefSeq; XP_012873883.1; XM_013018429.1.
DR   AlphaFoldDB; A0A1S3FB67; -.
DR   STRING; 10020.ENSDORP00000013072; -.
DR   GeneID; 105987231; -.
DR   KEGG; dord:105987231; -.
DR   CTD; 5991; -.
DR   InParanoid; A0A1S3FB67; -.
DR   OrthoDB; 2915941at2759; -.
DR   Proteomes; UP000081671; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR003150; DNA-bd_RFX.
DR   InterPro; IPR039779; RFX-like.
DR   InterPro; IPR007668; RFX1_trans_act.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR12619; RFX TRANSCRIPTION FACTOR FAMILY; 1.
DR   PANTHER; PTHR12619:SF20; TRANSCRIPTION FACTOR RFX3; 1.
DR   Pfam; PF04589; RFX1_trans_act; 1.
DR   Pfam; PF02257; RFX_DNA_binding; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51526; RFX_DBD; 1.
PE   4: Predicted;
KW   Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW   Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000081671};
KW   Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT   DOMAIN          158..233
FT                   /note="RFX-type winged-helix"
FT                   /evidence="ECO:0000259|PROSITE:PS51526"
FT   REGION          659..694
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   745 AA;  83228 MW;  1ED449F9670429C8 CRC64;
     MQTSETGSDT GSTVTLQTSV ASQAAVPTQV VQQVPVQQQV QQVQTVQQVQ HVYPAQVQYV
     EGSDTVYTNG AIRTTTYPYT ETQMYSQNTG GNYFDTQGSS AQVTTVVSSH SMVGTGGIQM
     GVTGGQLISS SGGTYLIGNS MENSGHAVTH TTRASPATLQ WLLDNYETAE GVSLPRSTLY
     NHYLRHCQEH KLDPVNAASF GKLIRSIFMG LRTRRLGTRG NSKYHYYGIR VKPDSPLNRL
     QEDMQYMAMR QQPMQQKQRY KPMQKVDGVA DGFTGSGQQT GTSVEQTVIA QSQHHQQFLD
     ASRALPEFGE VEISSLPDGT TFEDIKSLQS LYREHCEAIL DVVVNLQFSL IEKLWQTFWR
     YSPSTPTDGT TITESSNLSE IESRLPKAKL ITLCKHESIL KWMCNCDHGM YQALVEILIP
     DVLRPIPSAL TQAIRNFAKS LEGWLSNAMN NIPQRMIQTK VAAVSAFAQT LRRYTSLNHL
     AQAARAVLQN TSQINQMLND LNRVDFANVQ EQASWVCQCD DSMVQRLETD FKMTLQQQST
     LEQWAAWLDN VMMQALKPYE GRPSFPKAAR QFLLKWSFYS SMVIRDLTLR SAASFGSFHL
     IRLLYDEYMF YLVEHRVAQA TGETPIAVMG ETYLVDEKNT PIMELFISKL PNFGDLNAVS
     PGNLDKDEGS EVESEMDEEL DDSSEPQAKR EKTELSQAFP VGCMQPVLES SVQPGLLNPI
     HSEHIVTSTQ TIRQCSTTGN TYTAV
//