ID A0A1S3FC70_DIPOR Unreviewed; 748 AA.
AC A0A1S3FC70;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Amyloid beta A4 precursor protein-binding family A member 1 {ECO:0000313|RefSeq:XP_012873855.1};
GN Name=Apba1 {ECO:0000313|RefSeq:XP_012873855.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012873855.1};
RN [1] {ECO:0000313|RefSeq:XP_012873855.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012873855.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_012873855.1; XM_013018401.1.
DR AlphaFoldDB; A0A1S3FC70; -.
DR STRING; 10020.ENSDORP00000002947; -.
DR GeneID; 105987204; -.
DR KEGG; dord:105987204; -.
DR CTD; 320; -.
DR InParanoid; A0A1S3FC70; -.
DR OrthoDB; 2881953at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR CDD; cd22578; Mint1_CID; 1.
DR CDD; cd00992; PDZ_signaling; 2.
DR CDD; cd01208; PTB_X11; 1.
DR Gene3D; 2.30.42.10; -; 2.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR006020; PTB/PI_dom.
DR PANTHER; PTHR12345:SF14; AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY A MEMBER 1; 1.
DR PANTHER; PTHR12345; SYNTENIN RELATED; 1.
DR Pfam; PF00595; PDZ; 2.
DR Pfam; PF00640; PID; 1.
DR SMART; SM00228; PDZ; 2.
DR SMART; SM00462; PTB; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 2.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50106; PDZ; 2.
DR PROSITE; PS01179; PID; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000081671};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 368..554
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT DOMAIN 567..652
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 658..734
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 225..252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 297..346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..50
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..101
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 311..346
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 748 AA; 82848 MW; 5413F4A47A0C5CDA CRC64;
MNHLEGSAEV EVPDEAAGGE VNESVEADLE RPERQLGSQQ EEEERGECLA RSASTESGFH
NHTDTAEGDV IAAGRDDDDG DEEAERAQDP AHDPEDESAY AVQYRPEAEE YTEQAEAEHA
EAAHRRALPN HLHFHSLEHE EAMNAAYSGY VYTHRLFHRG EDEPYAEPYA DYGGLQEHVY
EEIGDAPELE ARDPDGLRLY EERERDEAAA AYRQEALGAR LHHYDERSDG ESDSPQRAAG
PAGDSGQRYS KEKRDAISLA IKDIKEAIEE VKTRTIRSPY TPDEPKEPIW VMRQDISPTR
DCDDQRPVDG DSPSPGSSSP LGAESSSTPL HPSDPAEAST NKESRKSLAS FPTYVEVPGP
CDPEDLIDGI IFAANYLGST QLLSDKTPSK NVRMMQAQEA VSRIKMAQKL AKSRKKAPEG
ESQPMTEVDL FISTQRIKVL NADTQETMMD HPLRTISYIA DIGNIVVLMA RRRMPRSNSQ
ENVEASHPAQ DGKRQYKMIC HVFESEDAQL IAQSIGQAFS VAYQEFLRAN GINPEDLSQK
EYSDLLNTQD MYNDDLIHFS KSENCKDVFI EKQKGEILGV VIVESGWGSI LPTVIIANMM
HGGPAEKSGK LNIGDQIMSL NGTSLVGLPL STCQSIIKGL KNQSRVKLNI VRCPPVTTVL
IRRPDLRYQL GFSVQNGIIC SLMRGGIAER GGVRVGHRII EINGQSVVAT PHEKIVHVLS
NAVGEIHMKT MPAAMYRLLT AQEQPVYI
//
