ID A0A1S3FG54_DIPOR Unreviewed; 376 AA.
AC A0A1S3FG54;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=E3 ubiquitin-protein ligase RNF133 {ECO:0000313|RefSeq:XP_012875476.1};
GN Name=Rnf133 {ECO:0000313|RefSeq:XP_012875476.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012875476.1};
RN [1] {ECO:0000313|RefSeq:XP_012875476.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012875476.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_012875476.1; XM_013020022.1.
DR AlphaFoldDB; A0A1S3FG54; -.
DR STRING; 10020.ENSDORP00000018697; -.
DR GeneID; 105988395; -.
DR KEGG; dord:105988395; -.
DR CTD; 168433; -.
DR InParanoid; A0A1S3FG54; -.
DR OrthoDB; 5474929at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd02122; PA_GRAIL_like; 1.
DR CDD; cd16802; RING-H2_RNF128-like; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR22765:SF38; E3 UBIQUITIN-PROTEIN LIGASE RNF133; 1.
DR PANTHER; PTHR22765; RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000081671};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT TRANSMEM 191..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 257..298
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 331..376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 331..352
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 353..371
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 376 AA; 42613 MW; ADFD8F9A0FD618E2 CRC64;
MNLRKIGTWE NNDTATIWLM KFSVLWLFSQ NCCRASAIWT AYMNISFHVG NRILSELGET
GVFGKSSSLK RVTGVLLPPE GKIQNACNPR TNFRRSKNAE TWLALIERGS CTFTQKIKVA
TEKGASGVII YNFPGTGNQI FPMFHKTFED TVVVMIGNLK GMEILHLIQE GVRVTVTVEV
GRKHIIWLNH YFISFMIATT AVFTYFISYH VRRVWIARMQ NRRWQRLTTN LKRAFSQLQL
RVLKEGDEEL NPNGDNCVVC FEPYKPNDTI RILTCKHFFH KNCIDPWILS HGTCPMCKCD
ILKALGVPGD IENGAESLQV LMANELLEAV SPREEEASNE LPPLRSDKVT QVDEHPTSPN
NDSQPDTVVG TVHPSP
//
