ID   A0A1S3FGV7_DIPOR        Unreviewed;       823 AA.
AC   A0A1S3FGV7;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Protocadherin gamma-A6 {ECO:0000313|RefSeq:XP_012875736.1};
GN   Name=Pcdhga6 {ECO:0000313|RefSeq:XP_012875736.1};
OS   Dipodomys ordii (Ord's kangaroo rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC   Dipodomyinae; Dipodomys.
OX   NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012875736.1};
RN   [1] {ECO:0000313|RefSeq:XP_012875736.1}
RP   IDENTIFICATION.
RC   TISSUE=Kidney {ECO:0000313|RefSeq:XP_012875736.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_012875736.1; XM_013020282.1.
DR   AlphaFoldDB; A0A1S3FGV7; -.
DR   GeneID; 105988611; -.
DR   KEGG; dord:105988611; -.
DR   CTD; 56109; -.
DR   InParanoid; A0A1S3FGV7; -.
DR   OrthoDB; 5402790at2759; -.
DR   Proteomes; UP000081671; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR   CDD; cd11304; Cadherin_repeat; 6.
DR   Gene3D; 2.60.40.60; Cadherins; 6.
DR   InterPro; IPR002126; Cadherin-like_dom.
DR   InterPro; IPR015919; Cadherin-like_sf.
DR   InterPro; IPR032455; Cadherin_C.
DR   InterPro; IPR020894; Cadherin_CS.
DR   InterPro; IPR013164; Cadherin_N.
DR   PANTHER; PTHR24028; CADHERIN-87A; 1.
DR   PANTHER; PTHR24028:SF107; PROTOCADHERIN GAMMA-A6; 1.
DR   Pfam; PF00028; Cadherin; 5.
DR   Pfam; PF08266; Cadherin_2; 1.
DR   Pfam; PF16492; Cadherin_C_2; 1.
DR   PRINTS; PR00205; CADHERIN.
DR   SMART; SM00112; CA; 6.
DR   SUPFAM; SSF49313; Cadherin-like; 6.
DR   PROSITE; PS00232; CADHERIN_1; 4.
DR   PROSITE; PS50268; CADHERIN_2; 6.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW   ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000081671};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           30..823
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5010240886"
FT   TRANSMEM        685..710
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          27..133
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          134..242
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          243..343
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          351..448
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          449..558
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          575..679
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
SQ   SEQUENCE   823 AA;  90648 MW;  D5C2BF65138B4E76 CRC64;
     MAALQRRRDC GELLWLFILL GWLWGIAAGQ IRYSIPEELE KGSFVGNITK DLGIQSKELA
     EHRVRVVSRD RTQLFSLNPR SGSLVTAGRI DREELCAQSP RCLVSFNILM EDKLNLFPVE
     VEILDVNDNA PRFLREALEV KILENSAPSS RFLLMEVYDP DVGMNSLQSF KLSSNSHFSV
     DVQSQAQGTK HPELVLEHAL DREVEATYHL VLTAMDGGDP VRSSMAQILV TVLDANDNAP
     VFTQSIYRVN VPENLPVGTL VLSVNATDQD EGIHAEVTYS FGKISQIFHL NALTGEISVS
     APLDYEECSL YELDVEARDQ PGLQDRAKVL ITILDVNDNE PEVVITSGSR TIAENAPPGT
     VVALFQVYDR DSGQNGQVTC SIPRNLPFEL ERSIDNYYRL VTNSILDQEQ VSLYNITVTA
     TDKGTPPLST EKLIYLSVAD TNDNPPMFSH SSYSVYVPEN NPRGTSIFSL KALDPDSEEN
     AQVIYSLAKE TPQGTPLSSY LSINPNTGVL YALCSFDYEE FRDLHLLVTA SDRGNPPLSS
     NVSLNLFILD QNDNAPEILY PAPPNDGSTG VELAPRSAEP GYLVTKVVAV DKDSGQNAWL
     SYRLLKASEP GLFMVGLHTG EVRTARALVD RDALKQSLVV SVQDHGQPPL SATVTLTVAV
     ADSIPDILAD LGHLEPPNNS DASDLTLYLV VAVAAVSCIF LAFVMVLLVF RLRHWYKSSL
     LKVPSEGFSS VPTSHFVGVE GVQAFLQTYS HEVSLTADSR KSHIIFPQPN YAHTLISQEG
     CEKNEPLLIQ DDSSFCKEEN SSVQVLCHSS EKLMQYNPDS FPL
//