ID A0A1S3FI87_DIPOR Unreviewed; 513 AA.
AC A0A1S3FI87;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Transcriptional activator protein Pur-alpha {ECO:0000313|RefSeq:XP_012875759.1};
GN Name=Pura {ECO:0000313|RefSeq:XP_012875759.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012875759.1};
RN [1] {ECO:0000313|RefSeq:XP_012875759.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012875759.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the PUR DNA-binding protein family.
CC {ECO:0000256|ARBA:ARBA00009251}.
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DR RefSeq; XP_012875759.1; XM_013020305.1.
DR AlphaFoldDB; A0A1S3FI87; -.
DR STRING; 10020.ENSDORP00000007807; -.
DR GeneID; 105988638; -.
DR KEGG; dord:105988638; -.
DR CTD; 5813; -.
DR InParanoid; A0A1S3FI87; -.
DR OrthoDB; 1040548at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0032422; F:purine-rich negative regulatory element binding; IEA:InterPro.
DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 3.10.450.700; -; 1.
DR Gene3D; 3.30.2450.30; -; 1.
DR InterPro; IPR006628; PUR-bd_fam.
DR PANTHER; PTHR12611; PUR-TRANSCRIPTIONAL ACTIVATOR; 1.
DR PANTHER; PTHR12611:SF2; TRANSCRIPTIONAL ACTIVATOR PROTEIN PUR-ALPHA; 1.
DR Pfam; PF04845; PurA; 1.
DR SMART; SM00712; PUR; 3.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000081671}.
FT REGION 1..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 81..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 172..211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 486..513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..24
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..100
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 172..188
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 486..501
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 513 AA; 55526 MW; BFB76052FD49D893 CRC64;
MLTRQRQRGR ALARDSEGRE RARRRPPRQQ LKRRDARAEG AGHGGGGERG ARADVAGSHA
RSAGLRADVW LPRLAVYGGG GGGERFPLGK EEEEGEPKGA PKSNRGTIAD IPAPSLLGIQ
AVQQRLPPFL PPPPAALLAA TSVLKLQLPL RWGTKKSIPD YNKISSQGTA KAAKGLANSD
NQGGGGGGSS CGGSRAATRR VPLPPPSSEG CRISREWLTG CGGCGGGGGG GGGSSGGGGG
APGGLQHETQ ELASKRVDIQ NKRFYLDVKQ NAKGRFLKIA EVGAGGNKSR LTLSMSVAVE
FRDYLGDFIE HYAQLGPSQP PDLAQAQDEP RRALKSEFLV RENRKYYMDL KENQRGRFLR
IRQTVNRGPG LGSTQGQTIA LPAQGLIEFR DALAKLIDDY GVEEEPAELP EGTSLTVDNK
RFFFDVGSNK YGVFMRVSEV KPTYRNSITV PYKVWAKFGH TFCKYSEEMK KIQEKQREKR
AACEQLHQQQ QQQQEETTAA TLLLQGEEEG EED
//
