ID A0A1S3FIN4_DIPOR Unreviewed; 325 AA.
AC A0A1S3FIN4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=GDNF family receptor alpha-3 {ECO:0000313|RefSeq:XP_012875767.1};
GN Name=Gfra3 {ECO:0000313|RefSeq:XP_012875767.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012875767.1};
RN [1] {ECO:0000313|RefSeq:XP_012875767.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012875767.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GDNFR family.
CC {ECO:0000256|ARBA:ARBA00005961}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_012875767.1; XM_013020313.1.
DR AlphaFoldDB; A0A1S3FIN4; -.
DR GeneID; 105988648; -.
DR KEGG; dord:105988648; -.
DR CTD; 2676; -.
DR InParanoid; A0A1S3FIN4; -.
DR OrthoDB; 3899332at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR Gene3D; 1.10.220.110; GDNF binding domain; 1.
DR InterPro; IPR016017; GDNF/GAS1.
DR InterPro; IPR037193; GDNF_alpha.
DR InterPro; IPR003438; GDNF_rcpt.
DR InterPro; IPR003505; GDNF_rcpt_A3.
DR PANTHER; PTHR10269:SF15; GDNF FAMILY RECEPTOR ALPHA-3; 1.
DR PANTHER; PTHR10269; GDNF RECEPTOR ALPHA; 1.
DR Pfam; PF02351; GDNF; 2.
DR PRINTS; PR01319; GDNFRALPHA3.
DR PRINTS; PR01316; GDNFRECEPTOR.
DR SMART; SM00907; GDNF; 2.
DR SUPFAM; SSF110035; GDNF receptor-like; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000256|ARBA:ARBA00023170,
KW ECO:0000313|RefSeq:XP_012875767.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000081671};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 87..164
FT /note="GDNF/GAS1"
FT /evidence="ECO:0000259|SMART:SM00907"
FT DOMAIN 173..265
FT /note="GDNF/GAS1"
FT /evidence="ECO:0000259|SMART:SM00907"
SQ SEQUENCE 325 AA; 36828 MW; 35413BB4C0AA68A6 CRC64;
MPKKLMKAML REMADEIKDQ IFKELNEFQE KMIVLGTNSS KEKKIYVSIP TGDYELDVSP
YDDTVTGKPW KMNLSKLKML KPDSDLCLKF TTLCILNDKC DRLRKAYGMA CSGPHCQRHI
CLAQLRNFFE KAAESHAQGL LLCPCAPTDK SCGERRRNTI APSCALPSEP PNCLELQSRC
LTDALCRSRL MDFQTHCHPL DILGTCATEQ SRCLRAYLGL IGTTMTPNFI SNFNTSVALS
CTCRGSGNLQ EECEQLERSF SHNSCLRKAI ATKMHFHSQL FSQDWAPPTF SVVQYQMENL
ALRTQARVPW LFSCTLTLVL LQSLW
//
