ID A0A1S3FRC8_DIPOR Unreviewed; 598 AA.
AC A0A1S3FRC8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=SHC-transforming protein 3 {ECO:0000313|RefSeq:XP_012878915.1};
GN Name=Shc3 {ECO:0000313|RefSeq:XP_012878915.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012878915.1};
RN [1] {ECO:0000313|RefSeq:XP_012878915.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012878915.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_012878915.1; XM_013023461.1.
DR AlphaFoldDB; A0A1S3FRC8; -.
DR STRING; 10020.ENSDORP00000005098; -.
DR GeneID; 105990929; -.
DR KEGG; dord:105990929; -.
DR CTD; 53358; -.
DR InParanoid; A0A1S3FRC8; -.
DR OMA; NTQRIPQ; -.
DR OrthoDB; 2903566at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR GO; GO:0001784; F:phosphotyrosine residue binding; IEA:Ensembl.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd01209; PTB_Shc; 1.
DR CDD; cd09925; SH2_SHC; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR006019; PID_Shc-like.
DR InterPro; IPR006020; PTB/PI_dom.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR035676; SHC_SH2.
DR PANTHER; PTHR10337; SHC TRANSFORMING PROTEIN; 1.
DR PANTHER; PTHR10337:SF4; SHC-TRANSFORMING PROTEIN 3; 1.
DR Pfam; PF00640; PID; 1.
DR Pfam; PF00017; SH2; 1.
DR PRINTS; PR00401; SH2DOMAIN.
DR PRINTS; PR00629; SHCPIDOMAIN.
DR SMART; SM00462; PTB; 1.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS01179; PID; 1.
DR PROSITE; PS50001; SH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000081671};
KW SH2 domain {ECO:0000256|ARBA:ARBA00022999, ECO:0000256|PROSITE-
KW ProRule:PRU00191}.
FT DOMAIN 153..318
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT DOMAIN 503..594
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 82..151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 598 AA; 64642 MW; 00239A2149452776 CRC64;
MLPRTKYNRF RNDSVTSVDD LLHSLSVSGG GRGSKVSAER TTRAATPYLV SGEGLRKASE
DGPGSLGHLL HKVSHLKLSS SGLRGLSSAG RERAGARLSG SCSAPSLAAR DSSAPPAPRA
PAVSMSTGRK GRPGDEPLPR PPRGVPHSSD QVLGPGVTYV VKYLGCIEVL RSMRSLDFST
RTQITREAIS RVCEAVPGAK GALKKRKPPS KMLSSILGKS NLQFAGMSIS LTISTASLNL
RTPDSKQIIA NHHMQSISFA SGGDPDTTDY VAYVAKDPVN RRACHILECC DGLAQDVIGS
IGQAFELRFK QYLQCPSKIP ALQDRMQSLD EPWTEEEGEG PDHPYYNSIP SKMPPPGGFL
DARLKTRPQT PDTAQFAGKE QTYYQGRHLG DTFGEDWQPT PIRQGSLDIY SMPEGKVNVA
PMGEAPTYIN TQHIPAQALP AAASSAESSP RKDLFDMKPF EDALKNQSLG PVLSKAASVE
CISPVSPRAP DAKMLEELDA EPWYQGEMSR KEAEGLLEKD GDFLVRKSTT NPGSFVLTGM
HNGQAKHLLL VDPEGTIRTK DRVFDSISHL IHHHLESSLP IVSAGSELCL QQPVERKQ
//
