ID   A0A1S3FX87_DIPOR        Unreviewed;       596 AA.
AC   A0A1S3FX87;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Ceramide kinase {ECO:0000313|RefSeq:XP_012881176.1};
GN   Name=Cerk {ECO:0000313|RefSeq:XP_012881176.1};
OS   Dipodomys ordii (Ord's kangaroo rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC   Dipodomyinae; Dipodomys.
OX   NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012881176.1};
RN   [1] {ECO:0000313|RefSeq:XP_012881176.1}
RP   IDENTIFICATION.
RC   TISSUE=Kidney {ECO:0000313|RefSeq:XP_012881176.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_012881176.1; XM_013025722.1.
DR   AlphaFoldDB; A0A1S3FX87; -.
DR   STRING; 10020.ENSDORP00000002630; -.
DR   GeneID; 105992712; -.
DR   KEGG; dord:105992712; -.
DR   CTD; 64781; -.
DR   InParanoid; A0A1S3FX87; -.
DR   OrthoDB; 7645at2759; -.
DR   Proteomes; UP000081671; Unplaced.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.200.40; -; 1.
DR   InterPro; IPR017438; ATP-NAD_kinase_N.
DR   InterPro; IPR045363; CERK_C.
DR   InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR   InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR   PANTHER; PTHR12358:SF25; CERAMIDE KINASE; 1.
DR   PANTHER; PTHR12358; SPHINGOSINE KINASE; 1.
DR   Pfam; PF19280; CERK_C; 1.
DR   Pfam; PF00781; DAGK_cat; 1.
DR   SMART; SM00046; DAGKc; 1.
DR   SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR   PROSITE; PS50146; DAGK; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|RefSeq:XP_012881176.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000081671};
KW   Transferase {ECO:0000313|RefSeq:XP_012881176.1}.
FT   DOMAIN          187..337
FT                   /note="DAGKc"
FT                   /evidence="ECO:0000259|PROSITE:PS50146"
FT   REGION          1..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        30..57
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   596 AA;  65955 MW;  94DF7117A93F19B3 CRC64;
     MTSGATEEAV QACPAAGEGG GAGLTRPGAP HRPGHPPTGP GLPAAPPTRL PGDREEPPIP
     SFPRRLRRLS GCPWRSWQSG KSALHLQKPG EEEEERVEMG IRKHRPYVCS LPVSELITVE
     ETDAHGKHSG SGRWQKMEKP YAFTVHCVKR ARHHRWKWAQ VTFWSTEEQL CQLWLQTLRE
     LLQRLTSRPK HLLVFINPFG GKGHGKRIYE RKVAPLFTLA SITTDIIITE HPNQAKETLY
     EMDVDAYDGI VCVGGDGMFS EVLHGLIGRT QKSAGVDQNH PRAALVPSPL RIGIIPAGST
     DCVCYSTVGT IDAETSALHI IVGDSLAMDV SSVHHGSTLL RYSVSLLGYG FYGDLIKDSE
     KKRWMGLVRY DFSGVKTFLS HHYYEGTVSF LPAQHTVGSP RDRKACHAGC FVCRQSKQQL
     EEEQKKALYG LENAEEVEEW QVVCGKFLAI NATNMSCACP RSPRGLSPAA HLGDGSSDLI
     LIRKCSRFNF LRFLVRHTNQ CDQFDFTFVE VYRVKRFQFT SKALEDGAHG LGGPGKQRFG
     PLCSDSPSCC CAAARGAWNC DGELLHTPAL EVRVHCQLVR LFARGIEETP KQESPS
//