ID A0A1S3FXS1_DIPOR Unreviewed; 178 AA.
AC A0A1S3FXS1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Protein FAM49B isoform X2 {ECO:0000313|RefSeq:XP_012880637.1};
GN Name=Fam49b {ECO:0000313|RefSeq:XP_012880637.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012880637.1};
RN [1] {ECO:0000313|RefSeq:XP_012880637.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012880637.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Interacts with RAC1 (GTP-bound form preferentially).
CC {ECO:0000256|ARBA:ARBA00011307}.
CC -!- SIMILARITY: Belongs to the CYRI family.
CC {ECO:0000256|ARBA:ARBA00005778}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_012880637.1; XM_013025183.1.
DR AlphaFoldDB; A0A1S3FXS1; -.
DR SMR; A0A1S3FXS1; -.
DR GeneID; 105992341; -.
DR CTD; 51571; -.
DR OrthoDB; 2785093at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0030833; P:regulation of actin filament polymerization; IEA:InterPro.
DR InterPro; IPR039789; CYRI.
DR InterPro; IPR009828; CYRIA/CYRIB_Rac1-bd.
DR PANTHER; PTHR12422:SF3; CYFIP-RELATED RAC1 INTERACTOR B; 1.
DR PANTHER; PTHR12422; UNCHARACTERIZED; 1.
DR Pfam; PF07159; CYRIA-B_Rac1-bd; 1.
PE 3: Inferred from homology;
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000081671}.
FT DOMAIN 1..174
FT /note="CYRIA/CYRIB Rac1 binding"
FT /evidence="ECO:0000259|Pfam:PF07159"
SQ SEQUENCE 178 AA; 20193 MW; 6B1EB5EC8FC79566 CRC64;
MTNPAIQNDF SYYRRTLSRM RINNVPAEGE NEVNNELANR MSLFYAEATP MLKTLSDATT
KFVSENKNLP IENTTDCLST MASVCRVMLE TPEYRSRFTN EETVSFCLRV MVGVIILYDH
VHPVGAFAKT SKIDMKGCIK VLKDQPPNSV EGLLNALRYT TKHLNDETTS KQIKSMLQ
//
