ID A0A1S3FYY7_DIPOR Unreviewed; 415 AA.
AC A0A1S3FYY7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Sprouty-related, EVH1 domain-containing protein 3 {ECO:0000313|RefSeq:XP_012881771.1};
GN Name=Spred3 {ECO:0000313|RefSeq:XP_012881771.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012881771.1};
RN [1] {ECO:0000313|RefSeq:XP_012881771.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012881771.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_012881771.1; XM_013026317.1.
DR AlphaFoldDB; A0A1S3FYY7; -.
DR STRING; 10020.ENSDORP00000006450; -.
DR GeneID; 105993149; -.
DR KEGG; dord:105993149; -.
DR CTD; 399473; -.
DR InParanoid; A0A1S3FYY7; -.
DR OrthoDB; 3031266at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009966; P:regulation of signal transduction; IEA:InterPro.
DR CDD; cd10574; EVH1_SPRED-like; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR023337; KBD.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041937; SPRE_EVH1.
DR InterPro; IPR007875; Sprouty.
DR InterPro; IPR000697; WH1/EVH1_dom.
DR PANTHER; PTHR11202:SF19; SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 3; 1.
DR PANTHER; PTHR11202; SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER; 1.
DR Pfam; PF05210; Sprouty; 1.
DR Pfam; PF00568; WH1; 1.
DR SMART; SM00461; WH1; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS51488; KBD; 1.
DR PROSITE; PS51227; SPR; 1.
DR PROSITE; PS50229; WH1; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000081671}.
FT DOMAIN 1..118
FT /note="WH1"
FT /evidence="ECO:0000259|PROSITE:PS50229"
FT DOMAIN 200..249
FT /note="KBD"
FT /evidence="ECO:0000259|PROSITE:PS51488"
FT REGION 122..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 180..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 253..293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 122..163
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 180..198
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 259..290
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 415 AA; 43548 MW; C687E10365E81C9A CRC64;
MSSRYMVRVR AVVMARDDSS GGWLPVGGGG LSQVSVCRVR GARPEGGARQ GHYVIHGERL
RDQKITLECT LRPGLVYNKV NPIFHHWSLG DCKFGLTFQS PAEADEFQKS LLSALAALSR
GSLTPSSSSS SSSPSQDTAE TPCPLTSHID SDSSSSHSRQ ETPPASAAAP IITVESASTF
GPAMSPQHRR SSAQSYPPLL PFTGIPEPSE PVAGAGGPGW GGRGYEDYRR SGPPAPLTLS
TCVVRFAKTG TLRGASPGPP VSLPAPLTEA VPPAPPARPP PGPGPTPVPA KASPEAEEAA
RCVHCRALFR RRADGRGGRC AEAPDPGRLL VRRLSCLWCA ESLLYHCLSD AEGDFSDPCA
CEPGHPRPAA RWAALAALSL AVPCLCCYAP LRACHWVASR CGCAGCGGRH EEAAR
//
