ID A0A1S3FZ68_DIPOR Unreviewed; 744 AA.
AC A0A1S3FZ68;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=B-cell receptor CD22 {ECO:0000256|ARBA:ARBA00040106};
DE AltName: Full=Sialic acid-binding Ig-like lectin 2 {ECO:0000256|ARBA:ARBA00041781};
GN Name=Cd22 {ECO:0000313|RefSeq:XP_012881670.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012881670.1};
RN [1] {ECO:0000313|RefSeq:XP_012881670.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012881670.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR RefSeq; XP_012881670.1; XM_013026216.1.
DR AlphaFoldDB; A0A1S3FZ68; -.
DR GeneID; 105993076; -.
DR CTD; 933; -.
DR OrthoDB; 4167621at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR46958; B-CELL RECEPTOR CD22; 1.
DR PANTHER; PTHR46958:SF1; B-CELL RECEPTOR CD22; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF13895; Ig_2; 1.
DR Pfam; PF13927; Ig_3; 3.
DR SMART; SM00409; IG; 6.
DR SMART; SM00408; IGc2; 5.
DR SUPFAM; SSF48726; Immunoglobulin; 6.
DR PROSITE; PS50835; IG_LIKE; 6.
PE 4: Predicted;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_012881670.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000081671};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 572..590
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 34..122
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 127..211
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 216..299
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 304..371
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 390..466
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 477..560
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 744 AA; 80986 MW; F9AA4EE943631784 CRC64;
MPDSGRLGLR LTSGPKLKWM EKFSLNVSKT PLPPRIQLPT EIRESQPLTA TCLLEFACPG
YPVQLWWSQE GSAHTSVSLS VQSIYTRSDL TFQAQWTDHG KTLTCQVRNF STILSKDSVK
LCVKHTPKLN ISISPHEATV KEGELVTMTC QVASSYPEYT ALSWLKDGVP LEGQGALTLV
LDSVTRAMGG KYQCQATNDV GLGLSEELTL RVLYAPEPST VHIHPSPAQE STSVELVCAA
SANPPARNFS WFHNGAALAG ETGEKVHFPS VLPRHAGAYA CLAYNSLGSG GMGSPAELDV
QYAPKMVEAV VENTAEIREG DPVTLSCHYN SSNPQVSHFE WRPRGPWEEP IPGVLTIPRV
AWDAGPMACA ACNQWCSWAV PVNLDVQYAP RGVEVRQSPL GELHAGQRVL LRCSVDRAQP
EAVHVLWMRN GSRVAEGSQL VLAAITPEDA GDYSCEASNA VGPAVSRAHA VQVLYAPRRL
RVSISPEAGV VEGRKVSLTC ESDANPPVWQ YAWFHGDSQQ LQFSGPTLRL EPAQVQHSGP
YWCQGANRLG IGRSPPHTLT VYYSPETIGR RTAVGIGGCI TLLILAIWGI KLRHKWKRSQ
SQQGLQEGSS NQSFFVRNKK VRHARRSEGP PSTGCLNPMM DDEVSYAVLR FPEADTPRQG
DLGTADAKAP ECLLMGDEAV TYSVLQRPLV GDYENVGKAA GAPGARAEER TGEDSVHYSE
LVLFGAGERR PRPEEVDYVT IAQS
//
