ID A0A1S3G0L6_DIPOR Unreviewed; 861 AA.
AC A0A1S3G0L6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Receptor-type tyrosine-protein phosphatase kappa isoform X4 {ECO:0000313|RefSeq:XP_012882346.1};
GN Name=Ptprk {ECO:0000313|RefSeq:XP_012882346.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012882346.1};
RN [1] {ECO:0000313|RefSeq:XP_012882346.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012882346.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR RefSeq; XP_012882346.1; XM_013026892.1.
DR AlphaFoldDB; A0A1S3G0L6; -.
DR GeneID; 105993590; -.
DR CTD; 5796; -.
DR OrthoDB; 2875525at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd00063; FN3; 2.
DR CDD; cd06263; MAM; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR000998; MAM_dom.
DR PANTHER; PTHR24051:SF11; PROTEIN-TYROSINE-PHOSPHATASE; 1.
DR PANTHER; PTHR24051; SUSHI DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00041; fn3; 2.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF00629; MAM; 1.
DR PRINTS; PR00020; MAMDOMAIN.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00409; IG; 1.
DR SMART; SM00137; MAM; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS00740; MAM_1; 1.
DR PROSITE; PS50060; MAM_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_012882346.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000081671};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..861
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010335417"
FT TRANSMEM 753..774
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 33..193
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 195..280
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 293..388
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 391..487
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 490..594
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
SQ SEQUENCE 861 AA; 95497 MW; E9909903A89A92B2 CRC64;
MDSAAPALPA FVALVLLSPW PLLGSAQGQF SAGGCTFDDG PGACDYHQDL YDDFEWVHVS
AQEPLYLPPE MPQGSYMIVD SSNHDPGEKA RLQLPTMKEN DTHCIDFSYL LYSQNGLNPG
TLNILVRVNK GPLANPIWNV TGFTGRDWLR AELAVSTFWP NEYQVIFEAE VSGGRSGYIA
IDDIQVLSYP CDKSPHFLRL GDVEVNAGQN ATFQCIATGR DAVHNKLWLQ RRNGEDIPVA
QTKNINHRRF AASFRLQEVT KTDQDLYRCV TQSERGSGVS NFAQLIVREP PRPIAPPQLL
GVGPTYLLIQ LNANSIIGDG PIILKEVEYR MTSGSWTETH AVNAPTYKLW HLDPDTEYEI
RVLLTRPGEG GTGLPGPPLI TRTKCAEPMR TPKTLKIAEI QARRIAVDWE SLGYNITRCH
TFNVTICYHY FRGHNESKAD CLDMDPKAPQ HVVSHLPPYT NVSLKMILTN PEGRKESEET
IIQTDEDLPG PVPIKSLQGT SFENKIFLNW KEPLDPNGII TQYEVSYSSI RSFDPAVPVA
GPPQTVSNLW NSTHHVFMHL HPGTTYQFFI RASTVKGFGP ATAINVTTNI SAPTLPDYEG
VDASLNETAT TITVLLRPAQ AKGAPISAYQ IVVEELHPHR TKREAGAMEC YQIPITYQNA
MSGGAPYYFA AELPPGNLPE PAPFTVGDNR TYQGFWNPPL APRKGYNIYF QAMSSVEKET
KTQCVRIATK AAATEEPEVI PDPAKQTDRV VKIAGISAGI LVFILLLLVV ILIVKKSKLA
KKRKDAMGNT RQEMTHMVNA MDRSYADQST LHAEDPLSIT FMDQHNFSPR LPNDPLVPTA
VLGRKNVYHG DNNSFFAISY L
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