ID A0A1S3G378_DIPOR Unreviewed; 222 AA.
AC A0A1S3G378;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Charged multivesicular body protein 2a {ECO:0000256|ARBA:ARBA00040870};
DE AltName: Full=Chromatin-modifying protein 2a {ECO:0000256|ARBA:ARBA00042902};
GN Name=Chmp2a {ECO:0000313|RefSeq:XP_012883261.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012883261.1};
RN [1] {ECO:0000313|RefSeq:XP_012883261.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012883261.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SNF7 family.
CC {ECO:0000256|ARBA:ARBA00006190}.
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DR RefSeq; XP_012883261.1; XM_013027807.1.
DR AlphaFoldDB; A0A1S3G378; -.
DR SMR; A0A1S3G378; -.
DR STRING; 10020.ENSDORP00000022526; -.
DR GeneID; 105994333; -.
DR KEGG; dord:105994333; -.
DR CTD; 27243; -.
DR InParanoid; A0A1S3G378; -.
DR OMA; RYAKKFM; -.
DR OrthoDB; 198578at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR GO; GO:1904930; C:amphisome membrane; IEA:Ensembl.
DR GO; GO:0000785; C:chromatin; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0000815; C:ESCRT III complex; IEA:Ensembl.
DR GO; GO:0000776; C:kinetochore; IEA:Ensembl.
DR GO; GO:0005828; C:kinetochore microtubule; IEA:Ensembl.
DR GO; GO:0005765; C:lysosomal membrane; IEA:Ensembl.
DR GO; GO:0030117; C:membrane coat; IEA:Ensembl.
DR GO; GO:0030496; C:midbody; IEA:Ensembl.
DR GO; GO:0032585; C:multivesicular body membrane; IEA:Ensembl.
DR GO; GO:0005643; C:nuclear pore; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0031210; F:phosphatidylcholine binding; IEA:Ensembl.
DR GO; GO:0019904; F:protein domain specific binding; IEA:Ensembl.
DR GO; GO:0097352; P:autophagosome maturation; IEA:Ensembl.
DR GO; GO:0045184; P:establishment of protein localization; IEA:Ensembl.
DR GO; GO:0010458; P:exit from mitosis; IEA:Ensembl.
DR GO; GO:1902774; P:late endosome to lysosome transport; IEA:Ensembl.
DR GO; GO:0010324; P:membrane invagination; IEA:Ensembl.
DR GO; GO:0061952; P:midbody abscission; IEA:Ensembl.
DR GO; GO:0007080; P:mitotic metaphase chromosome alignment; IEA:Ensembl.
DR GO; GO:0071985; P:multivesicular body sorting pathway; IEA:Ensembl.
DR GO; GO:1903723; P:negative regulation of centriole elongation; IEA:Ensembl.
DR GO; GO:0031468; P:nuclear membrane reassembly; IEA:Ensembl.
DR GO; GO:0001778; P:plasma membrane repair; IEA:Ensembl.
DR GO; GO:1903543; P:positive regulation of exosomal secretion; IEA:Ensembl.
DR GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR GO; GO:0051258; P:protein polymerization; IEA:Ensembl.
DR GO; GO:0010824; P:regulation of centrosome duplication; IEA:Ensembl.
DR GO; GO:1901673; P:regulation of mitotic spindle assembly; IEA:Ensembl.
DR GO; GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IEA:Ensembl.
DR GO; GO:0046761; P:viral budding from plasma membrane; IEA:Ensembl.
DR GO; GO:0039702; P:viral budding via host ESCRT complex; IEA:Ensembl.
DR Gene3D; 6.10.140.1230; -; 1.
DR InterPro; IPR005024; Snf7_fam.
DR PANTHER; PTHR10476; CHARGED MULTIVESICULAR BODY PROTEIN; 1.
DR PANTHER; PTHR10476:SF4; CHARGED MULTIVESICULAR BODY PROTEIN 2A; 1.
DR Pfam; PF03357; Snf7; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000081671}.
FT REGION 179..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 12..53
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 222 AA; 25134 MW; F2B86C623832E29E CRC64;
MDLLFGRRKT PEELLRQNQR ALNRAMRELD RERQKLETQE KKIIADIKKM AKQGQMDAVR
IMAKDLVRTR RYVRKFVLMR ANIQAVSLKI QTLKSNNSMA QAMKGVTKAM GTMNRQLKLP
QIQKIMMEFE RQAEIMDMKE EMMNDAIDDA MGDEEDEEES DAVVSQVLDE LGLSLTDELS
NLPSTGGSLS VAAGGKKAEA TASALADADA DLEERLKNLR RD
//
