ID   A0A1S3G8S2_DIPOR        Unreviewed;      1425 AA.
AC   A0A1S3G8S2;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Lipopolysaccharide-responsive and beige-like anchor protein isoform X3 {ECO:0000313|RefSeq:XP_012885216.1};
GN   Name=Lrba {ECO:0000313|RefSeq:XP_012885216.1};
OS   Dipodomys ordii (Ord's kangaroo rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC   Dipodomyinae; Dipodomys.
OX   NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012885216.1};
RN   [1] {ECO:0000313|RefSeq:XP_012885216.1}
RP   IDENTIFICATION.
RC   TISSUE=Kidney {ECO:0000313|RefSeq:XP_012885216.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_012885216.1; XM_013029762.1.
DR   STRING; 10020.ENSDORP00000016761; -.
DR   GeneID; 105995871; -.
DR   CTD; 987; -.
DR   OrthoDB; 5478899at2759; -.
DR   Proteomes; UP000081671; Unplaced.
DR   CDD; cd06071; Beach; 1.
DR   CDD; cd01201; PH_BEACH; 1.
DR   Gene3D; 1.10.1540.10; BEACH domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR000409; BEACH_dom.
DR   InterPro; IPR036372; BEACH_dom_sf.
DR   InterPro; IPR046851; NBCH_WD40.
DR   InterPro; IPR010508; NBEA-like_DUF1088.
DR   InterPro; IPR023362; PH-BEACH_dom.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR13743; BEIGE/BEACH-RELATED; 1.
DR   PANTHER; PTHR13743:SF64; LIPOPOLYSACCHARIDE-RESPONSIVE AND BEIGE-LIKE ANCHOR PROTEIN; 1.
DR   Pfam; PF02138; Beach; 1.
DR   Pfam; PF06469; DUF1088; 1.
DR   Pfam; PF20426; NBCH_WD40; 1.
DR   Pfam; PF14844; PH_BEACH; 1.
DR   SMART; SM01026; Beach; 1.
DR   SMART; SM00320; WD40; 5.
DR   SUPFAM; SSF81837; BEACH domain; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS50197; BEACH; 1.
DR   PROSITE; PS51783; PH_BEACH; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000081671};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW   WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           17..1425
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5010189733"
FT   DOMAIN          635..743
FT                   /note="BEACH-type PH"
FT                   /evidence="ECO:0000259|PROSITE:PS51783"
FT   DOMAIN          762..1051
FT                   /note="BEACH"
FT                   /evidence="ECO:0000259|PROSITE:PS50197"
FT   REPEAT          1337..1378
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REGION          125..147
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          161..190
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          332..358
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        332..347
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1425 AA;  157845 MW;  1952E6B1CCC36DF7 CRC64;
     MSSGGILRQC LRLVCAVAVR NCLECQQHSQ LKARGDSAKG LKTIHCLVPL GKLAAKSPVD
     IVTGGISPVR DLDRLLQDMD INRLRAVVFR DIEDSKQAQF LALAVVYFIS VLMVSKYRDI
     LEPQHERQSQ SFKETSSENG SASLPDVENI PAAFSPLTLS SVEESVESTS STRRRDSGLG
     EETASGLSSH VSVSSPAVPL GVSAGPDAIS EVLCTLSLEV NKSQETKNDG GDELDNKAVP
     VSKNVNVKDI LRSLVNIPAD GVTVDPALLP PACLGALGDL SAEQPVQFRS FDRSVVIATK
     KSAVLPSTLS TSAPTTAPTN AVSVVSSVDS AQASDVGGES PGSRPSSAKL PSVPAVGSVP
     EDPVSNMSIT ERLEHALEKA APLLREIFVD FAPFLSRTLL GSHGQELLIE GTSLVCMKSS
     SSVVELVMLL CSQEWQNSIQ KNAGLAFIEL VNEGRLLSQT MKDHLVRVAN EAEFILSRQR
     AEDIHRHAEF ESLCAQYSAD KREEEKVCDH LIRAAKYRDH VTATQLIQKM INILTDKHGA
     WGNSAVSRPR EFWRLDYWED DLRRRRRFVR NPLGSTHPEA TLKTAVEHAA DEDILAKGKQ
     SIKSQALGNQ NSENEILLEG DDDTLSSVDE KDLENLAGPV SLSTPAQLVA PSVVVKGTLS
     VTSSELFFEV DEEDPNFKKI DPKILAYTEG LHGKWLFSEI RSIFSRRYLL QNTALEIFMA
     NRVAIMFNFP DPATVKKVVN CLPRVGVGTS FGLPQTRRIS LASPRQLFKA SNMTQRWQHR
     EVSNFEYLMF LNTIAGRSYN DLNQYPVFPW VITNYESEEL DLTLPSNFRD LSKPIGALNP
     KRAAFFAERF ESWEDDQVPK FHYGTHYSTA SFVLAWLLRI EPFTTYFLNL QGGKFDHADR
     TFSSVSRAWR NSQRDTSDIK ELIPEFYYLP EMFVNFNNYN LGVMDDGTVV SDVELPPWAK
     TSEEFVRINR LALESEFVSC QLHQWIDLIF GYKQQGPEAV RALNVFYYLT YEGAVNLNSI
     TDPVLREAVE AQIRSFGQTP SQLLIEPHPP RGSAMQASPL MFTDQAQQDV IMVLKFPSNS
     PVTHVAANTQ PGLATPAVIT VTANRLFAVN KWHNLPAHQG AVQDQPYQLP VEIDPLIASN
     TGMHRRQITD LLDQSIQVHS QCFVITSDNR YILICGFWDK SFRVYSTDTG KLIQVVFGHW
     DVVTCLTRSE SYIGGNCYIL SGSRDATLLL WYWNGKSSGI GDNPGSETTT PRAILTGHDY
     EITCAAVCAE LGLVLSGSQE GPCLIHSMNG DLLRTLEGPG HCLKPKLIQA SREGHCVIFY
     ENGCLCTFSV NGKLQATVET DDHIRAMQLS RDGQYLLTGG DHGVVMVWQA SDFKQLFTYP
     GCDAGIRAMA LSYDQRCVIA GMASGSIVLF YNDFNRWHHE YQTRY
//