ID   A0A1S3GBK7_DIPOR        Unreviewed;      1888 AA.
AC   A0A1S3GBK7;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=CDK5 regulatory subunit-associated protein 2 {ECO:0000256|ARBA:ARBA00020479};
GN   Name=Cdk5rap2 {ECO:0000313|RefSeq:XP_012885624.1};
OS   Dipodomys ordii (Ord's kangaroo rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC   Dipodomyinae; Dipodomys.
OX   NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012885624.1};
RN   [1] {ECO:0000313|RefSeq:XP_012885624.1}
RP   IDENTIFICATION.
RC   TISSUE=Kidney {ECO:0000313|RefSeq:XP_012885624.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Golgi
CC       apparatus {ECO:0000256|ARBA:ARBA00004555}.
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DR   RefSeq; XP_012885624.1; XM_013030170.1.
DR   GeneID; 105996172; -.
DR   CTD; 55755; -.
DR   OrthoDB; 2912560at2759; -.
DR   Proteomes; UP000081671; Unplaced.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005815; C:microtubule organizing center; IEA:InterPro.
DR   GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.
DR   InterPro; IPR042791; CDK5RAP2.
DR   InterPro; IPR012943; Cnn_1N.
DR   PANTHER; PTHR46930; CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 2; 1.
DR   PANTHER; PTHR46930:SF1; CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 2; 1.
DR   Pfam; PF07989; Cnn_1N; 1.
PE   4: Predicted;
KW   Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000081671}.
FT   DOMAIN          59..131
FT                   /note="Centrosomin N-terminal motif 1"
FT                   /evidence="ECO:0000259|Pfam:PF07989"
FT   REGION          265..289
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1020..1058
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1336..1387
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1869..1888
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          59..176
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          587..617
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1201..1235
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1397..1431
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1479..1541
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1591..1618
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        1035..1050
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1361..1384
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1888 AA;  213794 MW;  C082E3E83BA609DF CRC64;
     MDSVLEEDVT LPGTLSGCSG LVSTLPDNLN GISISAGLGN GGLPKASEEK VSPTRARNMK
     DFENQITELK KENFNLKLRI YFLEERMQQE FDGPTEQVYR TNIELKVEVE SLKRELHERE
     KLLIKASKAV ESLAEGGGSE IQRVKEDAQK KVQQVEDLLT RRIRLLEGDV KAAQAELEKA
     FVGTEMEKAL RLSLESQLAA MKKMQEGDLE VALALDEKDR LIEELKLSLK SKEALIQCLK
     EGKSQMASPD ENVASGELGG LSTALKEAKE RDEDEATQTE RQKERNHFEE RIQALQEDLR
     EKEREIATEK KNSLKRDKAI QGLTTALKSK ERAVEELNAE IKDLNAAFAK AKEASQKTQT
     QGSEDHQAAL AEKEALLAEL HSENLTKNTE NHRLRRNMKK MSQELGELQQ EKARLEQELD
     EARREGSRGA RTANDLRNEV EKLRNEVNER EKAVENHYQS LLSESNRKLH SQEQIIKRLR
     ESANQKDLML RKFSEKDLEA IQQSHHLMTT EDLEFGSEGL ITEKCSSQQS PGSKLIFSQE
     KLHSDYEELV EVLKKEQDIY AHLVKSLQDP NSVNNLQAEL GHIFALRKQL EQDVLAHRNL
     QKALEEQISE IRRREEEPFS FYSDQTSYLS ICLEEPDRFQ VERFSQEELK RKVSDLIQLV
     KELYTDNQHL KKTIFDISCM GVQGNGRLES TQQTELLASK EDEDMIKIEE DGENNFQSDQ
     RLQQSNEMIE DHAKGGCKNG YLRHTDANIL DHDGVPKPGH RGDQRLEELL GLLTPFFHEK
     ASLLLESRNR PDLLKALQEL LLGRIYLAEQ EASGEHVDGK TEKMLKQIAV QLRRELEHSV
     PASPFAKPHD GLKSPWRAQL VKTSEVDRTE MKNVSVQTVA VEEDPLRFTY EGQKKAWEDV
     VADATFSSEP QPENLCGMPG MQTTLLSLPC VTNKEAKKSR LPILMKSAQS LGHAYRFLAT
     QEVVAKLQGQ IMELQGELKE CKTHNKQLHH KLILVEALME GKPAPDQMLL NVPAAQPLVE
     AASQDSPGKH EGTKSSPSAQ RDKDQHTNLE TDSEIYSPDD LAVLPTHKEN SEDFLDPTSA
     ATCLDSKSQL SVKVSVSESD PSGDLDISHD TEYLKQKICD LETELEGYRN FLFQLQKHSQ
     CSEAIITVLC GTEGAQDGLN KPKGSTDEEE MTFSSLHQVR YVKHMKILRP LTPEMIDSRM
     LESLRQQLVQ QEYELQKEQN LNLELFSEIH NLQNKFRDLS PARYDSLVQS QARELSLQRQ
     QIKDSHDICV IYRQHMSTMI KAFEELLQAS DVDACVAEGF QEQLNQCAEL LQRLEKLLLH
     GKSAGVELGS QNELMERTEE DNPAYQDILP KSPEPPASHI LSDDEMSEKS FLSRDPKQDS
     ETEKISAVSS RFPQDLLMEH IQEIRTLRKR LEESIKTNEK LRKQLERQGS ELEQGPTNTL
     THGSELHSSL ISEIHFLRKQ NQALSMMLVK GSKDKQKEND KLRESLSKTA ASFEHLQQEC
     AGVREENERL WKDLAERESH NQQLARELSR TQEEVMSKQQ LLSENNELLQ SLRVELKVYQ
     KLDEEHRQRW QEAQAEPSGE GWKGQDPLRD LHGLLTEMQA LRAQLEKSIE TNSTLRSRLE
     EQLAQGANKA QEGALIPATQ ALCIPEWSLQ LDKHDGDKCP VPSENSFDST QAVTVKSETP
     LLSGNDVDSF SCDSGSLATN TAQVSFLVTS HRLWASSSGR HILGLAEDYD ALCKQISQGH
     KLLAEMDLQT REALNPTCGE PGTKGPHLVT LSKFVFSVGA AKLVLEEASR LLQLLWRVSL
     PPNGQCSLHC EQIGEMKSEI TKLYKTLFEQ EKKLQNSVKL LQQSKHQEKV IFDQLAVTHK
     VLRKARGNLE LRPGGAHPGT SSPSRSGF
//