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Database: UniProt
Entry: A0A1S3GCR0_DIPOR
LinkDB: A0A1S3GCR0_DIPOR
Original site: A0A1S3GCR0_DIPOR 
ID   A0A1S3GCR0_DIPOR        Unreviewed;       454 AA.
AC   A0A1S3GCR0;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   16-OCT-2019, entry version 18.
DE   SubName: Full=GA-binding protein alpha chain isoform X1 {ECO:0000313|RefSeq:XP_012886489.1, ECO:0000313|RefSeq:XP_012886490.1, ECO:0000313|RefSeq:XP_012886491.1};
GN   Name=Gabpa {ECO:0000313|RefSeq:XP_012886489.1,
GN   ECO:0000313|RefSeq:XP_012886490.1, ECO:0000313|RefSeq:XP_012886491.1};
OS   Dipodomys ordii (Ord's kangaroo rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha;
OC   Heteromyidae; Dipodomyinae; Dipodomys.
OX   NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012886490.1};
RN   [1] {ECO:0000313|RefSeq:XP_012886489.1, ECO:0000313|RefSeq:XP_012886490.1, ECO:0000313|RefSeq:XP_012886491.1}
RP   IDENTIFICATION.
RC   TISSUE=Kidney {ECO:0000313|RefSeq:XP_012886489.1,
RC   ECO:0000313|RefSeq:XP_012886490.1};
RG   RefSeq;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594387}.
CC   -!- SIMILARITY: Belongs to the ETS family.
CC       {ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594391}.
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DR   RefSeq; XP_012886489.1; XM_013031035.1.
DR   RefSeq; XP_012886490.1; XM_013031036.1.
DR   RefSeq; XP_012886491.1; XM_013031037.1.
DR   Ensembl; ENSDORT00000014903; ENSDORP00000014021; ENSDORG00000014904.
DR   GeneID; 105996813; -.
DR   CTD; 2551; -.
DR   OMA; DLFWTHL; -.
DR   OrthoDB; 526256at2759; -.
DR   Proteomes; UP000081671; Genome assembly.
DR   GO; GO:0000790; C:nuclear chromatin; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0033613; F:activating transcription factor binding; IEA:Ensembl.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:Ensembl.
DR   GO; GO:0000978; F:RNA polymerase II proximal promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0001825; P:blastocyst formation; IEA:Ensembl.
DR   GO; GO:1903351; P:cellular response to dopamine; IEA:Ensembl.
DR   GO; GO:0045653; P:negative regulation of megakaryocyte differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.10.150.50; -; 1.
DR   InterPro; IPR000418; Ets_dom.
DR   InterPro; IPR024668; GABP_asu_N.
DR   InterPro; IPR003118; Pointed_dom.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR016312; TF_GA-bd_asu.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00178; Ets; 1.
DR   Pfam; PF11620; GABP-alpha; 1.
DR   Pfam; PF02198; SAM_PNT; 1.
DR   PIRSF; PIRSF001703; GABP_alpha; 1.
DR   PRINTS; PR00454; ETSDOMAIN.
DR   SMART; SM00413; ETS; 1.
DR   SMART; SM00251; SAM_PNT; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   SUPFAM; SSF54236; SSF54236; 1.
DR   PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR   PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR   PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR   PROSITE; PS51433; PNT; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000081671};
KW   DNA-binding {ECO:0000256|RuleBase:RU004019,
KW   ECO:0000256|SAAS:SAAS00594397};
KW   Nucleus {ECO:0000256|RuleBase:RU004019,
KW   ECO:0000256|SAAS:SAAS00594400};
KW   Reference proteome {ECO:0000313|Proteomes:UP000081671}.
FT   DOMAIN      168    251       PNT. {ECO:0000259|PROSITE:PS51433}.
FT   DOMAIN      320    400       ETS. {ECO:0000259|PROSITE:PS50061}.
FT   REGION      296    316       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
SQ   SEQUENCE   454 AA;  51437 MW;  A958921D9F3F1934 CRC64;
     MTKREAEELI EIEIDGTEKT ECTEESIVEQ TYTPAECISQ AIDINEPIGN LKKLLEPRLQ
     CSLDAHEICL QDIQLDPERS LFDQGVKTDG TVQLSVQVIS YQGIEPKLNI LEIVKTAETV
     EVVIDPDEHQ AEAEAHLVEE AQVITLDGTK HITTITDETS EQVTRWAAAL EGYRKEQERL
     GIPYDPIQWS TDQVLHWVVW VMKEFSMTDI DLTTLNISGR ELCSLSQEDF FQRVPRGEIL
     WSHLELLRKY VLASQEQQMN EIVTIDQPVQ IIPASVQSAT PTTIKVINSS TKAAKVQRAP
     RISGEDRSSP GNRTGNNGQI QLWQFLLELL TDKDARDCIS WVGDEGEFKL NQPELVAQKW
     GQRKNKPTMN YEKLSRALRY YYDGDMICKV QGKRFVYKFV CDLKTLIGYS AAELNRLVTE
     CEQKKLAKMQ LHGIAQPVTA VALATASLQT EKDN
//
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