ID A0A1S3GKT6_DIPOR Unreviewed; 425 AA.
AC A0A1S3GKT6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=AP-1 complex subunit mu-2 isoform X1 {ECO:0000313|RefSeq:XP_012889421.1};
GN Name=Ap1m2 {ECO:0000313|RefSeq:XP_012889421.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012889421.1};
RN [1] {ECO:0000313|RefSeq:XP_012889421.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012889421.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the adaptor complexes medium subunit family.
CC {ECO:0000256|ARBA:ARBA00005324, ECO:0000256|PIRNR:PIRNR005992}.
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DR RefSeq; XP_012889421.1; XM_013033967.1.
DR AlphaFoldDB; A0A1S3GKT6; -.
DR GeneID; 105999075; -.
DR KEGG; dord:105999075; -.
DR CTD; 10053; -.
DR InParanoid; A0A1S3GKT6; -.
DR OrthoDB; 6959at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR GO; GO:0030131; C:clathrin adaptor complex; IEA:UniProtKB-UniRule.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd14835; AP1_Mu_N; 1.
DR Gene3D; 3.30.450.60; -; 1.
DR Gene3D; 2.60.40.1170; Mu homology domain, subdomain B; 2.
DR InterPro; IPR036168; AP2_Mu_C_sf.
DR InterPro; IPR022775; AP_mu_sigma_su.
DR InterPro; IPR001392; Clathrin_mu.
DR InterPro; IPR018240; Clathrin_mu_CS.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR InterPro; IPR028565; MHD.
DR PANTHER; PTHR10529; AP COMPLEX SUBUNIT MU; 1.
DR PANTHER; PTHR10529:SF234; AP-1 COMPLEX SUBUNIT MU-2; 1.
DR Pfam; PF00928; Adap_comp_sub; 1.
DR Pfam; PF01217; Clat_adaptor_s; 1.
DR PIRSF; PIRSF005992; Clathrin_mu; 1.
DR PRINTS; PR00314; CLATHRINADPT.
DR SUPFAM; SSF49447; Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor; 1.
DR SUPFAM; SSF64356; SNARE-like; 1.
DR PROSITE; PS00990; CLAT_ADAPTOR_M_1; 1.
DR PROSITE; PS00991; CLAT_ADAPTOR_M_2; 1.
DR PROSITE; PS51072; MHD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR005992};
KW Reference proteome {ECO:0000313|Proteomes:UP000081671};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005992}.
FT DOMAIN 168..423
FT /note="MHD"
FT /evidence="ECO:0000259|PROSITE:PS51072"
SQ SEQUENCE 425 AA; 48330 MW; 96926F7DADAF50DB CRC64;
MSASAVFILD VKGKPLISRN YKGDVPMSEI ERFMPLLMQR EEEGALTPLL SHGRVHFLWI
KHSNLYLVAT TLKNANASLV YSFLYKTVEV FCEYFKELEE ESIRDNFVIV YELLDELMDF
GYPQTTDSKI LQEYITQQSN KLETGKSRVP PTVTNAVSWR SEGIKYKKNE VFIDVIESVN
LLVNANGSVL LSEIVGTIKL KVFLSGMPEL RLGLNDRVLF ELTGLSGSKN KSVELEDVKF
HQCVRLSRFD NDRTISFIPP DGDFELMSYR LSTQVKPLIW IESVIEKFSH SRVEIMVKAK
GQFKKQSVAN GVEIAVPVPS DADSPRFKTS VGSAKYVPEK NVVIWSIKSF PGGKEYLMRA
HFGLPSVEKE EVEGRPPIGV KFEIPYFTVS GIQVRYMKII EKSGYQALPW VRYITQSGDY
QLRTS
//
