ID A0A1S3GL02_DIPOR Unreviewed; 261 AA.
AC A0A1S3GL02;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Interleukin-1 receptor-associated kinase 1-binding protein 1 {ECO:0000313|RefSeq:XP_012889558.1};
GN Name=Irak1bp1 {ECO:0000313|RefSeq:XP_012889558.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012889558.1};
RN [1] {ECO:0000313|RefSeq:XP_012889558.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012889558.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the IRAK1BP1 family.
CC {ECO:0000256|ARBA:ARBA00005509}.
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DR RefSeq; XP_012889558.1; XM_013034104.1.
DR AlphaFoldDB; A0A1S3GL02; -.
DR STRING; 10020.ENSDORP00000025049; -.
DR GeneID; 105999156; -.
DR KEGG; dord:105999156; -.
DR CTD; 134728; -.
DR InParanoid; A0A1S3GL02; -.
DR OMA; TQTATRE; -.
DR OrthoDB; 2943966at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0035591; F:signaling adaptor activity; IEA:Ensembl.
DR GO; GO:0007249; P:canonical NF-kappaB signal transduction; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0043123; P:positive regulation of canonical NF-kappaB signal transduction; IEA:Ensembl.
DR Gene3D; 3.30.110.170; Protein of unknown function (DUF541), domain 1; 1.
DR Gene3D; 3.30.70.2970; Protein of unknown function (DUF541), domain 2; 1.
DR InterPro; IPR030312; IRAK1BP1.
DR InterPro; IPR007497; SIMPL/DUF541.
DR PANTHER; PTHR18842; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR18842:SF2; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1-BINDING PROTEIN 1; 1.
DR Pfam; PF04402; SIMPL; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Kinase {ECO:0000313|RefSeq:XP_012889558.1};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Receptor {ECO:0000313|RefSeq:XP_012889558.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000081671};
KW Transferase {ECO:0000313|RefSeq:XP_012889558.1}.
SQ SEQUENCE 261 AA; 29169 MW; B55F02292DD53328 CRC64;
MSLPQAPPSR VFVQLVPWVD RGQEHNEVSG GEVLRGVRQP VSTQVPAGTR EVHVSGTAEV
SAGPNRAQVT VRMRSTKEAA AEAKKSVGRR LDYITQSLRR QGLQAENIAV TRDFRRVENA
YHMEAEVCIT FTEFEKMQNI CSFLVEKLDS SVVIEPPQFY HAPGAAENLR RQACLVAVEN
AWRKAQEVCH LVGQTLGKPL LIKEEETKEW EGQIEEHPSS GPLSSLTVQQ KIKSATLYAA
SKVFVTFEVK GKEKKKKHLR N
//
