ID A0A1S3GLW1_DIPOR Unreviewed; 877 AA.
AC A0A1S3GLW1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Vomeronasal type-2 receptor 116-like {ECO:0000313|RefSeq:XP_012888987.1};
GN Name=LOC105998743 {ECO:0000313|RefSeq:XP_012888987.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012888987.1};
RN [1] {ECO:0000313|RefSeq:XP_012888987.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012888987.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_012888987.1; XM_013033533.1.
DR AlphaFoldDB; A0A1S3GLW1; -.
DR GeneID; 105998743; -.
DR KEGG; dord:105998743; -.
DR InParanoid; A0A1S3GLW1; -.
DR OrthoDB; 5516580at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15283; 7tmC_V2R_pheromone; 1.
DR CDD; cd06365; PBP1_pheromone_receptor; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR InterPro; IPR004073; GPCR_3_vmron_rcpt_2.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR PANTHER; PTHR24061:SF547; VOMERONASAL 2, RECEPTOR 118-RELATED; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR01535; VOMERONASL2R.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170,
KW ECO:0000313|RefSeq:XP_012888987.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000081671};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..35
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 36..877
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010328041"
FT TRANSMEM 605..628
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 640..663
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 675..699
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 711..736
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 764..787
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 799..819
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 831..854
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 605..869
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 877 AA; 98378 MW; 60739FF767E9CF95 CRC64;
MGFTSSQNSS VANASMMFPL ISTLLLLQLP LLVSSLEGTA CFSRMKRRAH MDGDVMIAGF
FPLYTLGTDH SNSDSSLDEA KKQFVFKYYQ LVLALAFAVE EINKNSDFLH NMTLGFDIYN
ADLKAWSAFE NPFIWLSGHK KIPNYTCMAE RNFVAVLAGT SGMTSAEIGT LLELYRFPQV
KKGVILPFGA FDHVLSDHGK FPSLYQMSPK DTSLAIAMVS LLLHFSWNWV GLLISEDENG
LWILAELREK MYKNRICIAF EHVIPGSSMT QVFNMMAIQN QINKSSANVL IIYGNKEYLL
SLMTYLGQFL MTSKVWLLNS KCDLSIGRKY FMSGSFHVPL MLSRHHGDIS GFTDFIREVN
PSVYPEDFYL ARLWFLFFNC SHFESDCVMW KNCPEDSSLE WLPGQIFDMS MSEESYNTYN
AVYAVAHALH EMLLHQTEEA TMVNGRWMVP SPAQMRHFLK NVQFYNLAGD QVILDEERKL
EAEYDILNIW NFPEGLELKV KIGKFSPYAP YHQLSVSKDM IEWAIGATES PHSVCSESCV
PGFRKSFQGG KAVCCFDCTS CLDNEISNRT DMEQCMKCPD DQYANKKRTQ CLPKAASFLA
HDEPLGMGLV CMALCLSTFT ALILGVFVKY QDTPIVKANN LALSYILLIS LIFCFLCSLL
FIGQPNTVSC ILQQITFGVV FTVAVSTVLA KTVTVVLAFK ATSPGKRMRW LLVSGAPNFI
IPICTLIQVT LCGLWLGASP PFVDTDAHSE HGHVIILCNK GSLTAFYCVL GYLVFLALTS
FTVAYLARNL PDTFNEAKFL TFSMLVFCSV WVTFLPVYHS AKGKVMVAVE VFSILSSSAG
FLGCIFAPKC YIILLRPDRN SLHSFKGKMH TGRNEPS
//
