ID A0A1S3GMZ0_DIPOR Unreviewed; 552 AA.
AC A0A1S3GMZ0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Rhotekin isoform X2 {ECO:0000313|RefSeq:XP_012890070.1};
GN Name=Rtkn {ECO:0000313|RefSeq:XP_012890070.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012890070.1};
RN [1] {ECO:0000313|RefSeq:XP_012890070.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012890070.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_012890070.1; XM_013034616.1.
DR AlphaFoldDB; A0A1S3GMZ0; -.
DR GeneID; 105999565; -.
DR CTD; 6242; -.
DR OrthoDB; 5393023at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd13249; PH_rhotekin2; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR012966; AHD.
DR InterPro; IPR011072; HR1_rho-bd.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR21538; ANILLIN/RHOTEKIN RTKN; 1.
DR PANTHER; PTHR21538:SF19; RHOTEKIN; 1.
DR Pfam; PF08174; Anillin; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00742; Hr1; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS51860; REM_1; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01207};
KW Reference proteome {ECO:0000313|Proteomes:UP000081671}.
FT DOMAIN 10..85
FT /note="REM-1"
FT /evidence="ECO:0000259|PROSITE:PS51860"
FT DOMAIN 296..403
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 505..552
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 522..552
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 552 AA; 61322 MW; A5B849A1D6A8825C CRC64;
MQDRLHILED LNMLYIRQMA QSLEDTELQR KLDHEIRMRE GACKLLAACS QREQTLEATK
SLLVCNSRIL SYMGELQRRK EAQVLGKTSR RPSDSRLPAE RTPCRGRVCI SDLRIPLMWK
DTEYFKNKGD LHRWAVFLLL QLEEQIQDTE MILVDRTLTD ISFQNNVLFT EAGPDFELRL
ELYGACVDEE GALAGAPKRL ATKLSSSLGR SSGKRVRASL DSAAGSASST ILLPTPAVGG
PRYHLLAHTT LTLAAVQDGF RTHDLTLASH EENPAWLPLY GSVCCRLAAQ PLCMTQPTAS
GTLRVQQAGE LQNGAQVYGV LKGTNLFCYH RPEDADTGED PLLTIAINKE TRVRAGEPDQ
APGRPLTLSI SNQYGDDEVT HTLQTETREA LQNWMEALWQ LFFDMSQWKQ CCDEVMKIET
PAPRKPPQAL AKQGSLYHEM AIEPLDDIAA VTDILAQREG ARLESPPPWL AMFTDQPALP
SPCSPASVTP APSWTHPLPW GRPRTFSLDA VPSDHSPGAS RLASPLPNQR SPQSRGLCSS
KGPFRTWLQS PV
//
