ID A0A1S3GP57_DIPOR Unreviewed; 257 AA.
AC A0A1S3GP57;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=HLA class II histocompatibility antigen, DP beta 1 chain isoform X1 {ECO:0000313|RefSeq:XP_012890480.1};
GN Name=LOC105999877 {ECO:0000313|RefSeq:XP_012890480.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012890480.1};
RN [1] {ECO:0000313|RefSeq:XP_012890480.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012890480.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the MHC class II family.
CC {ECO:0000256|ARBA:ARBA00007394}.
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DR RefSeq; XP_012890480.1; XM_013035026.1.
DR AlphaFoldDB; A0A1S3GP57; -.
DR STRING; 10020.ENSDORP00000019866; -.
DR GeneID; 105999877; -.
DR KEGG; dord:105999877; -.
DR OrthoDB; 3785866at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR GO; GO:0042613; C:MHC class II protein complex; IEA:UniProtKB-KW.
DR GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR GO; GO:0002504; P:antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; IEA:UniProtKB-KW.
DR CDD; cd21003; IgC1_MHC_II_beta_HLA-DP; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003006; Ig/MHC_CS.
DR InterPro; IPR003597; Ig_C1-set.
DR InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR InterPro; IPR014745; MHC_II_a/b_N.
DR InterPro; IPR000353; MHC_II_b_N.
DR PANTHER; PTHR19944:SF46; HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DP BETA 1 CHAIN; 1.
DR PANTHER; PTHR19944; MHC CLASS II-RELATED; 1.
DR Pfam; PF07654; C1-set; 1.
DR Pfam; PF00969; MHC_II_beta; 1.
DR SMART; SM00407; IGc1; 1.
DR SMART; SM00921; MHC_II_beta; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS00290; IG_MHC; 1.
PE 3: Inferred from homology;
KW Adaptive immunity {ECO:0000256|ARBA:ARBA00023130};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunity {ECO:0000256|ARBA:ARBA00022859};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW MHC II {ECO:0000256|ARBA:ARBA00023182};
KW Reference proteome {ECO:0000313|Proteomes:UP000081671};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..257
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010380253"
FT TRANSMEM 225..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 123..211
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 257 AA; 29474 MW; FFC9F08624C3FDB6 CRC64;
MILQVPKVAW PITLMVSLVM WCNSMAQSRA TPENYVLLSL DECYALNGTQ RYVERNIYNR
EEIVRFDSEV GEYRAVTELG RPSAEYWNSQ QDFLEQKRAE VDTVCRHNYE LDEGFTLKRR
VQPKVHVSPS KKGSLEHHNM LVCRVTDFYP GNIEIKWFRN GQEEKDGVVS TSLVHNGDWT
FQIMVMLEMT PQQGDVYTCH VEHPSLDGPV TVEWRAQSDS ARSKMLTGVG GFVLGLIFLT
VGTIMRVRSK KAPQAPR
//
