ID A0A1S3GRD2_DIPOR Unreviewed; 291 AA.
AC A0A1S3GRD2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Homeobox protein EMX1 {ECO:0000313|RefSeq:XP_012891240.1};
GN Name=Emx1 {ECO:0000313|RefSeq:XP_012891240.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012891240.1};
RN [1] {ECO:0000313|RefSeq:XP_012891240.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012891240.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the EMX homeobox family.
CC {ECO:0000256|ARBA:ARBA00007397}.
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DR RefSeq; XP_012891240.1; XM_013035786.1.
DR AlphaFoldDB; A0A1S3GRD2; -.
DR STRING; 10020.ENSDORP00000006515; -.
DR GeneID; 106000506; -.
DR KEGG; dord:106000506; -.
DR CTD; 2016; -.
DR InParanoid; A0A1S3GRD2; -.
DR OrthoDB; 903523at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR020479; Homeobox_metazoa.
DR PANTHER; PTHR24339; HOMEOBOX PROTEIN EMX-RELATED; 1.
DR PANTHER; PTHR24339:SF26; HOMEOBOX PROTEIN EMX1; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00024; HOMEOBOX.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000081671}.
FT DOMAIN 191..251
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 193..252
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 49..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 250..291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 250..266
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 291 AA; 31441 MW; 67DD4D70DC9BC106 CRC64;
MCMTGCTPRK AAEPGRPALP GAPLPRPTPA ATTMFQPAAK RGFTIESLVA KDGGTGGGTG
SGGAGSHPLA AAASEEPLRP TALNYPHPSA AEAAFVSGFP SAAAAAGAGR SLYGGPELVF
PEAMNHPALT VHPAHQLGAS PLQPPHSFFG AQHRDPLHFY PWVLRNRFFG HRFQASDVPQ
DGLLLHGPFA RKPKRIRTAF SPSQLLRLER AFEKNHYVVG AERKQLAGSL SLSETQVKVW
FQNRRTKYKR QKLEEEGPES EQKKKGSHHI NRWRIATKQA NGEDIDVTSN D
//
