ID A0A1S3GXR4_DIPOR Unreviewed; 285 AA.
AC A0A1S3GXR4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Hepatic leukemia factor isoform X3 {ECO:0000313|RefSeq:XP_012893576.1};
GN Name=Hlf {ECO:0000313|RefSeq:XP_012893576.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012893576.1};
RN [1] {ECO:0000313|RefSeq:XP_012893576.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012893576.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the bZIP family. PAR subfamily.
CC {ECO:0000256|ARBA:ARBA00009208}.
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DR RefSeq; XP_012893576.1; XM_013038122.1.
DR AlphaFoldDB; A0A1S3GXR4; -.
DR GeneID; 106003263; -.
DR CTD; 3131; -.
DR OrthoDB; 5354784at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd14695; bZIP_HLF; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR InterPro; IPR040223; PAR_bZIP.
DR PANTHER; PTHR11988:SF28; HEPATIC LEUKEMIA FACTOR; 1.
DR PANTHER; PTHR11988; THYROTROPH EMBRYONIC FACTOR RELATED; 1.
DR Pfam; PF07716; bZIP_2; 1.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; Leucine zipper domain; 1.
DR PROSITE; PS50217; BZIP; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000081671}.
FT DOMAIN 215..278
FT /note="BZIP"
FT /evidence="ECO:0000259|PROSITE:PS50217"
FT REGION 29..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 82..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 247..281
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 29..43
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..99
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 285 AA; 31891 MW; FBF8386F33B6E48A CRC64;
MTLWGLSFGP MRVHAFGISV TNADHPAAFS KDKDKEKKLD DESNSPTVPQ SAFLGPTLWD
KTLPYDGDTF QLEYMDLEEF LSENGIPPSP SQHDHSPHTP GLQPASAAVP SVMDLSSRPS
APLHPGIPSP NCMQSPIRPG QLLPANRNTP SPIDPDTIQV PVGYEPDPAD LALSSIPGQE
MFDPRKRKFS EEELKPQPMI KKARKVFIPD DLKQDDKYWA RRRKNNMAAK RSRDARRLKE
NQIAIRASFL EKENSALRQE VADLRKELGK CKNILAKYEA RHGPL
//
