ID A0A1S3GYB3_DIPOR Unreviewed; 284 AA.
AC A0A1S3GYB3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Homeobox protein Hox-B13 {ECO:0000313|RefSeq:XP_012893254.1};
GN Name=Hoxb13 {ECO:0000313|RefSeq:XP_012893254.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012893254.1};
RN [1] {ECO:0000313|RefSeq:XP_012893254.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012893254.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the Abd-B homeobox family.
CC {ECO:0000256|ARBA:ARBA00006317}.
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DR RefSeq; XP_012893254.1; XM_013037800.1.
DR AlphaFoldDB; A0A1S3GYB3; -.
DR STRING; 10020.ENSDORP00000007854; -.
DR GeneID; 106003044; -.
DR KEGG; dord:106003044; -.
DR CTD; 10481; -.
DR InParanoid; A0A1S3GYB3; -.
DR OMA; HPPDGCA; -.
DR OrthoDB; 728401at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005667; C:transcription regulator complex; IEA:Ensembl.
DR GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0008327; F:methyl-CpG binding; IEA:Ensembl.
DR GO; GO:1990837; F:sequence-specific double-stranded DNA binding; IEA:Ensembl.
DR GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR GO; GO:0060743; P:epithelial cell maturation involved in prostate gland development; IEA:Ensembl.
DR GO; GO:0060527; P:prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; IEA:Ensembl.
DR GO; GO:0040008; P:regulation of growth; IEA:Ensembl.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR022067; HoxA13_N.
DR PANTHER; PTHR45804:SF6; HOMEOBOX PROTEIN HOX-B13; 1.
DR PANTHER; PTHR45804; SEGMENTATION PROTEIN FUSHI TARAZU-LIKE PROTEIN; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF12284; HoxA13_N; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000081671}.
FT DOMAIN 214..274
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 216..275
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
SQ SEQUENCE 284 AA; 30721 MW; F3BCDFD13353972D CRC64;
MEPGNYATLD GTKDIEGLLG AGGGRNLVAH SPLSSHPAAP TLMPAVNYAP LDLPGSAEPP
KQCHPCPGVP QGASPAPVPY GYFGGGYYSC RVSRSSLKPC AQTATLAAYP TETPAAGEEY
PSRPTEFAFY PGYPGPYQPM ASYLDVSVVQ TLGAPGEPRH DSLLPVDSYQ PWALAGGWNS
QMCCQGEQNP PGPFWKAAFS DSSAQHPSDG CAFRRGRKKR IPYSKGQLRE LEREYAANKF
ITKDKRRKIS ATTSLSERQI TIWFQNRRVK EKKVLAKVKT SATP
//
