ID A0A1S3GZJ3_DIPOR Unreviewed; 2897 AA.
AC A0A1S3GZJ3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Nucleosome-remodeling factor subunit BPTF isoform X1 {ECO:0000313|RefSeq:XP_012893377.1};
GN Name=Bptf {ECO:0000313|RefSeq:XP_012893377.1};
OS Dipodomys ordii (Ord's kangaroo rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae;
OC Dipodomyinae; Dipodomys.
OX NCBI_TaxID=10020 {ECO:0000313|Proteomes:UP000081671, ECO:0000313|RefSeq:XP_012893377.1};
RN [1] {ECO:0000313|RefSeq:XP_012893377.1}
RP IDENTIFICATION.
RC TISSUE=Kidney {ECO:0000313|RefSeq:XP_012893377.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_012893377.1; XM_013037923.1.
DR GeneID; 106003129; -.
DR KEGG; dord:106003129; -.
DR CTD; 2186; -.
DR OrthoDB; 2878869at2759; -.
DR Proteomes; UP000081671; Unplaced.
DR GO; GO:0016589; C:NURF complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd05509; Bromo_gcn5_like; 1.
DR CDD; cd15559; PHD1_BPTF; 1.
DR CDD; cd15560; PHD2_3_BPTF; 2.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 3.
DR InterPro; IPR038028; BPTF.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR018501; DDT_dom.
DR InterPro; IPR028941; WHIM2_dom.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45975; NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF; 1.
DR PANTHER; PTHR45975:SF2; NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF02791; DDT; 1.
DR Pfam; PF00628; PHD; 3.
DR Pfam; PF15613; WSD; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00571; DDT; 1.
DR SMART; SM00249; PHD; 3.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 3.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS50827; DDT; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 3.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000081671};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 104..164
FT /note="DDT"
FT /evidence="ECO:0000259|PROSITE:PS50827"
FT DOMAIN 254..301
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 2660..2711
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 2718..2769
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 2795..2865
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 1..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 424..553
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 782..801
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 855..937
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1004..1085
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1106..1130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1172..1192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1210..1255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1268..1331
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1401..1497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1768..1797
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1954..1975
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2026..2064
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2137..2333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2508..2528
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2587..2650
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1817..1844
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2414..2444
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..51
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..69
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..93
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 424..491
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 492..517
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 864..903
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 910..937
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1013..1035
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1038..1052
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1054..1083
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1106..1129
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1172..1190
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1277..1305
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1306..1331
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1402..1453
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1463..1485
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2137..2200
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2207..2333
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2508..2524
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2593..2623
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2627..2650
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2897 AA; 322670 MW; 48B1A15842D9C7C2 CRC64;
MVSEEDEEEE EEEGDADETQ DSEEDDEEEM EEDEDDSDYP EEMEDDDDDA SYCTESSFRS
HSTYSSTPGR RKPRVHRPRS PILEEKDIPP LEFPKSSEDL MVPNEHIMNV IAIYEVLRNF
GTVLRLSPFR FEDFCAALVS QEQCTLMAEM HVVLLKAVLR EEDTSNTTFG PADLKDSVNS
TLYFIDGMTW PEVLRVYCES DREYHHVLPY QEAEDYPYGP VENKIKVLQF LVDQFLTTNI
AREELMSEGV IQYDDHCRVC HKLGDLLCCE TCSAVYHLEC VKPPLEEVPE DEWQCEVCVA
HKVPGVTDCV AEIQKNKPYI RHEPIGYDRS RRKYWFLNRR LIIEEDTENE NEKKIWYYST
KVQLAELIDC LDKDYWEAEL CKTLEEMREE MHRHMDITED LTNKARGSNK SFLAAANEEI
LDSIRAKKGD TDNDKSPEEV EKDKNETENN NCKEAEPSRE EFEDQSCEKE TDGRASDDSR
EPGKSEEPTE VGDKGNSVSA NLGDNTTNAS SEETSPCEGR SPEGCLSETH DSSNMAEKKV
ASELPQDVPG DFRLEKSNGE VAESPGAGRG ASGSTRIITR LRNPDSKLSQ LKNQQVAAAA
HEANKQFKEG KEVLVVNSQG EISRLSTKKE VVMKGNINNY FKLGQEGKYR VYHNQYSTNS
FALNKHQHRE DHDKRRHLAH KFCLTPAGEF KWNGSVHGSK VLTISTLRLT ITQLESNIPS
SFLHPNWASH RANWIKAVQM CSKPREFALA LAILECAVKP VVMLPIWRES LGHTRLHRMT
SIEREEKEKV KKKEKKQEEE ETMQQATWVK YTFPVKHQVW KQKGEEYRVT GYGGWSWISK
THVYRFVPKL PGNTNVNYRK PLEGMKNNGD ENMDESDKQK GLQSPKKIKT ESDCEKKDTA
KGAGQSEVDT SKTTEKKEED VKELLDSEND KSFKEEAMEV DQEEVKAESH VNCQESSPVD
VVNVSEGFHL RTCYKKKTKS SKLDGLLERR IKQFTMEEKQ RLEKMKLEGG IKGSGKSSTT
SLRDLSDSPI TTKAKEGCQN DLLRDEPSPV VNNEKCEESI QGCSQSDSSA LGISDSSLTP
SKPYSKRRLL DDVSIRTLGT NYQKQNSVDN DIDESLSEST SQGQDLSKSK TKGGALFIDV
SKPARTDDSG TLRFKTRKPL LEEENDNFIS SSETALLPSG PKNASNRDAP SLSKAMDFDG
KLVCDEYNNS TLENSSDTMS IQDSSEEDMV VQNSGESISE QFLTPEQDTE SSEPLRCEFV
SKSTGNCDDR LQGKVTEANG KKTSQQQSSE ERPMNKCADQ ANLKNITDKR NSENRESERK
GPKSTFQING KDKKAKIYSK GDCLKEIPES KVVSGNAESR VNNVNKIIPE NDIKPLTVKE
PSMKPFINGD VIMEELSEKN NLETNSRVPS SSEAEGNYQD SLKSLPSTKE SDSTQMTPPS
SCPESNSFNQ VEDMEVETPE VKKLTPSSVT SGEESNLSND FTDENGLPTH KAENINGDSK
RKTVITEVTT MTSTVATESK TVIKVAKGDK QTVVSSTENC AKSTVTTTTT TVTKLSTPST
DSTEDIISVK EQSKTVVTTT VTDSLTTAGG TLVTSMTVSK EYSTRDKVKL MKFSRPKKAR
SGTALPSYRK FITKSSKKSI FVLPNDDLKK LARKGGIREV PYFNYNAKPA LDIWPYPSPR
PTFGITWRYR LQTVKSLAGV SLMLRLLWAS LRWDDMAAKA PPGGGTTRTE TSETEITTTE
IIKRRDVGPY GIRSEYCIRK IICPIGVPEA PKETPTPQRK GLRSSALRPK RPETPKQTGP
VIIETWVAEE ELELWEIRAF AERVEKEKAQ AVEQQAKKRL EQQKPTVIAA STTSSPNSTT
STISPAQKVM VAPISGSVTP GTKMVLTTKV GSPATVTFQQ NKNFHQTFAT WVKQGQSNSG
VVQVQQKVLG IIPSSTGTSQ QTFTSFQPRT ATVTIRPNTS GSGGTTSPSQ VITGPQIRPG
MTVIRTPLQQ STLGKAIIRT PVMVQPGAPQ QVVTQIIRGQ PVSTAISAPS TASSTPGQKS
ITSGAAGTSL QSSASSAPRP QQGQVKLTMA QLTQLTQGHG GNQGLTVVIQ GQGQTTGQLQ
LIPQGVTILP GPGQQLMQAA MPNGTVQRFL FTPLATTTTT ASTSTTVSTT AGSGEQKQDK
LSPQTQVQPA KTLPPAPSSS VSPAEAQPQT AQLSAQPQPQ SYPQPQSPTQ PEVQDQPEVQ
PQTAVSSHVP SEAQPAQAQS SRPQVAAQCQ PQTNVQGQSP VRVQSPPQTR IRPSTPSQVS
PGQQSQVQTS ASQPIPIQPH TSLPIPSQGQ PQSQPQVQSS TQTLSAGQTL SQVTVSSPSC
PQLQIPQPQP QVIAVPQLQQ QVQVLSQIQP QVVAQIQAQQ GGVPQQLKLQ LPIQIQQSSA
VQPHQIQNVV TVQAASVQEQ LQRAQQLRDQ QQKKKQQQIE IKREHTLQAS NQSEVIQKQV
VMKHNAVIEH LKQKKPMTPA EREENQRMIV CNQVMKYILD KIDKEEKQAA KKRKREESVE
QKRSKQNASK LSALLFKHKE QLKAEILKKR ALLDKDLQIE VQEELRRDLK MKKEKDMVQV
AQASAVAAPS PPVVVTAPTP TAPPPSPPVV PGLQSPGLPV PPLPGASQKR KREEDKDSNS
KSKKKKVIST TSKETKKDTK LYCICKTPYD ESKFYIGCDL CTNWYHGECV GITEKEAKKM
DVYICNDCKR AQEGSSEELY CICRTPYDES QFYIGCDRCQ NWYHGRCVGI LQSEAELIDE
YVCPQCQSTE DAMTVLTPLT EKDYEGLKRV LRSLQAHKMA WPFLEPVDPN DAPDYYRVIK
EPMDLATMEE RVQRRYYEKL TEFVADMTKI FDNCRYYNPS DSPFYQCAEV LESFFVQKLK
GFKASRSHNN KLQSSAS
//
