ID A0A1S3H285_LINUN Unreviewed; 1038 AA.
AC A0A1S3H285;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Adhesion G-protein coupled receptor G6 isoform X2 {ECO:0000313|RefSeq:XP_013379586.1};
GN Name=LOC106151053 {ECO:0000313|RefSeq:XP_013379586.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013379586.1};
RN [1] {ECO:0000313|RefSeq:XP_013379586.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013379586.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_013379586.1; XM_013524132.1.
DR AlphaFoldDB; A0A1S3H285; -.
DR EnsemblMetazoa; XM_013524132.1; XP_013379586.1; LOC106151053.
DR GeneID; 106151053; -.
DR OrthoDB; 2962018at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR CDD; cd15040; 7tmB2_Adhesion; 1.
DR Gene3D; 2.60.220.50; -; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR046338; GAIN_dom_sf.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR017983; GPCR_2_secretin-like_CS.
DR InterPro; IPR000203; GPS.
DR InterPro; IPR026906; LRR_5.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR045860; Snake_toxin-like_sf.
DR PANTHER; PTHR12011; ADHESION G-PROTEIN COUPLED RECEPTOR; 1.
DR PANTHER; PTHR12011:SF437; GPS DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR Pfam; PF01825; GPS; 1.
DR Pfam; PF13306; LRR_5; 1.
DR PRINTS; PR00249; GPCRSECRETIN.
DR SMART; SM00303; GPS; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF57302; Snake toxin-like; 1.
DR PROSITE; PS00650; G_PROTEIN_RECEP_F2_2; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR PROSITE; PS50221; GPS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_013379586.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 717..742
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 754..771
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 791..811
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 823..845
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 865..893
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 914..935
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 941..964
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 718..965
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
FT REGION 983..1012
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1038 AA; 114749 MW; 3C08BD432E98BC24 CRC64;
MQSNTTIQRI EEFAFEGLFK LISLSIKSSV ENIYRNTFVG LRSLTNLTLG TVQYIAPDAF
INTPRLSSLV LTMNCIPPAI AVYTFLQQRH SQSHIIDSIH CTQGGSLRQA VEALNVNLEL
PFSNNCYTCT NVSLANSCLS QRCASAFSSC SDLIATTGRG ISITKECINL DACMTRTAEI
NPASSQNHSC CLGDNCNRQG LIEMSLARQT YIVHILFTHD ISSSSRAYWN LWTIFQTKLQ
KVLYEVMPRI HEVEVTSVMP SPVVGFNGTV SYVRIRTTVS SISNESVTRM NISNAISTAK
KNNQFMDVAL NGMYFKDGSL GVCLHSIDSS NKGNYTWQDR WINLTTITRS LSLPCRYNLG
NLPATAVRQC TLDIPTGIVY WLPPNHDNCM TTQRKVLLDL NDTKVDQDNV EEISGSLRNA
TSSEELSEGE VEIATGLLDR ILALNSTHVA RVAHDVVHTQ SNLLGSGQDS LLKSETNSQS
VNRILRGIDT FAEKVDISGT NLTIVAPNLA VSVVSANASD PEFSGLGFDS VSSGRNTNEN
VVRLVGSENE PVPDVADVGI RLPRTLFIGL NVTQQASASR VHFVVYQQNT FFKVLASVSN
SPGSVKTNTS VYPYVDINGH IIAGSVVGLT VQNLADPVTI SFKHLEREKE TVNNSQCVFW
DFSANSGQGG WSGRGCRLAG DQPGNRTVCQ CDHLTNFALL VDVFGSGSAI DPLNRRILMI
VTYVGCGLSV LGLLLTIISY LAYTKLRKDT PSKILIQLCF ALLGLNVVYV TGTQDLRNLF
VCKTVAILLH YFLLATLMWM LIEAFYMYLA LVKVFQTYYR KLLLKFAIVG WGVPLVIVAI
TLAINIDNYN YYTGYEEAFC WLTVIPMYVT VITPVAVTVV INFVAFGLVF HQVRSHVQQK
KITKTQKASS VSQVRGALGI MALLGLTWVF AFFTFSAKFI VFHYLFAIFN SLQGLFVFIF
HCFLKHDVRM MWMRSLPCCP KPKDSSTFNS SSKVPNRVST EMTTTSSRNN SFHSMSVGEV
NVKVPLNNAY QTSKGKIY
//
