ID A0A1S3H5F3_LINUN Unreviewed; 635 AA.
AC A0A1S3H5F3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=UPF0489 protein C5orf22 homolog {ECO:0000313|RefSeq:XP_013381197.1};
GN Name=LOC106152229 {ECO:0000313|RefSeq:XP_013381197.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013381197.1};
RN [1] {ECO:0000313|RefSeq:XP_013381197.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013381197.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- SIMILARITY: Belongs to the UPF0489 family.
CC {ECO:0000256|ARBA:ARBA00007099}.
CC -!- SIMILARITY: Belongs to the sulfatase family.
CC {ECO:0000256|ARBA:ARBA00008779}.
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DR RefSeq; XP_013381197.1; XM_013525743.1.
DR AlphaFoldDB; A0A1S3H5F3; -.
DR STRING; 7574.A0A1S3H5F3; -.
DR EnsemblMetazoa; XM_013525743.1; XP_013381197.1; LOC106152229.
DR GeneID; 106152229; -.
DR KEGG; lak:106152229; -.
DR InParanoid; A0A1S3H5F3; -.
DR OrthoDB; 2908272at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR Gene3D; 3.30.1120.10; -; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR000917; Sulfatase_N.
DR InterPro; IPR024131; UPF0489.
DR PANTHER; PTHR13225; MISEXPRESSION SUPPRESSOR OF RAS 6; 1.
DR PANTHER; PTHR13225:SF3; UPF0489 PROTEIN C5ORF22; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR Pfam; PF12640; UPF0489; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000085678}.
FT DOMAIN 493..585
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
SQ SEQUENCE 635 AA; 70990 MW; DE0FC83E2CD2B66A CRC64;
MSAPLETHVS ELKRYKNTPV VVVENHNEAL PHIYRSIGSK HLPLEGITLI HLDAHPDLLI
PKDIMADQVF DKQKLFESLS IENWIIPAVY AGHISDIVWV KPPWAKQMDD QETACCVGKH
KTTKKIMISC PENYFISELL FAPEEDLLEK KTLHLKVLTM DSSTELKAAL KGDRSLGHIT
ESVSKCCCET VQCGIVCDDS KKMAGIVCSV CCNAELEQAA NTNSREPSDK NYSKQNLLHA
PGVKRVLLDE ERDNKDDQIK RVKTDYGSGQ ISGGSSSKDR WNVKNDSIVT RIVSSLEKAS
SKAYILDIDL DFYSTQNPFK IAYTEKQFEI LNRLYYFKRP SLGREAEGTR EREAQLNFLQ
NVFKDLSTGK TFHEIKTSTQ EKDLQKMKLV EELVTDLQKN TASIDFEWLH EVGCTCDDTE
LPHHISSPEE IIALVRATKS PLELLPVNPI MITISRLLKT PSPNILRSLT ATEGQLELSH
YKICTYHFFS VAMMSVIDEG VANITKALTD SGIMDNTFFL FLSDNGGQYG SGNNYPLRGA
KSTFFEGGMR TPAFVSGGLL KKKGYTHNGL FHIADWTPTI LSLAGGDVTG ENLDGIDMTK
TVLEGANSSR DEIIHFLSQR NLPDSPPVRQ QGVIR
//
