ID A0A1S3H882_LINUN Unreviewed; 932 AA.
AC A0A1S3H882;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Neuronal PAS domain-containing protein 4 isoform X2 {ECO:0000313|RefSeq:XP_013382208.1};
GN Name=LOC106152998 {ECO:0000313|RefSeq:XP_013382208.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013382208.1};
RN [1] {ECO:0000313|RefSeq:XP_013382208.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013382208.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_013382208.1; XM_013526754.1.
DR AlphaFoldDB; A0A1S3H882; -.
DR EnsemblMetazoa; XM_013526754.1; XP_013382208.1; LOC106152998.
DR GeneID; 106152998; -.
DR OrthoDB; 614770at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd19697; bHLH-PAS_NPAS4_PASD10; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR PANTHER; PTHR23043; HYPOXIA-INDUCIBLE FACTOR 1 ALPHA; 1.
DR PANTHER; PTHR23043:SF24; NEURONAL PAS DOMAIN-CONTAINING PROTEIN 4; 1.
DR Pfam; PF14598; PAS_11; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50888; BHLH; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000085678}.
FT DOMAIN 1..54
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT DOMAIN 76..140
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 236..271
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT REGION 405..466
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 500..531
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 608..630
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 798..834
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 430..465
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 804..834
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 932 AA; 102341 MW; B61AAC939ED31032 CRC64;
MMFRSTKGAS KVRRDQINNE ILVVRDLLPL PESARQRLSQ LQIMSLACIF IRKSNYFARL
FGNPGYSVEG PFEFAQTLPG FLLVATRDGK MLYLSENVTE YLGHSMVDMM TQGDSIYDII
DKRDHTTVQS QLLQTSFGES QNQNVRSFFC RMNIARTLRR QSSIGDQKIM HVHGQFIQPM
IRDHYGNQPV FLALCSPLIT PETKETALQN NTMVFKSIHS LDMKYMEISQ RGEHHLGVTT
EDVTGRSWYS LLHPEDAQEA RDKHVQLIHS SHEMGCMLTV RLIRNDNTCI WVNTVMHIRQ
PYISDNGEAA IMCINQVISE NEAPYFKMQS QIYTAQMARN SEFMYSQPTS YSPQRCLSQS
IPPEGVPYAL TTTPVATMDP YSSGFSTSPN QTNYGGQFSL RTAPQHYLGD STSGSYTHPD
IALPPRGSLG SFSESPSEYS RGSSPGLQSV FSPSAASQFS WPEQPGSSIM ADPMHCTLAD
PMKSTLGDPL QSCVTETLQQ PSGIKRKSED PHPSCQPSKM LRVGHSHSDD SQGGMGGIGS
GFGSFPTEAS FLSAPFFSSP EGGNSGSTSF VYGSMQVLTQ NSYPSSTTTQ QALKAKLSMM
CMAKSNATKP LTDFQPPTPE SPKDQHPLKT TKEAVATETA TVPDSYLTPD SSPLHIHGDF
LLGDHKETTK FQLEEVIATI TKNISQEPVA DLEKFEDDEK HLLPVIDADV VDECLNSKTS
SSQAVLRNQS LTSCTPSVLT SLPSQNCSTS VAKKATKTAA THGLKMTDED KTNQFLPVIN
VMEIENYFNH FDDDSRDSTH SFESHASPRP SSTGMGSSPI QGHMSPDPSC AGTTETSYEN
LLETVGFTGD ISFLIESFPV PTTTTDAMSL MDANNVLGDS LIGDCFPATT SWSPLHQQNT
PPSYGVIVSN QELSQQLGDV NPPPSYGGPT MQ
//
