ID A0A1S3HAI9_LINUN Unreviewed; 478 AA.
AC A0A1S3HAI9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Acetyl-CoA hydrolase {ECO:0000256|ARBA:ARBA00017958};
DE EC=3.1.2.1 {ECO:0000256|ARBA:ARBA00011920};
DE AltName: Full=Acetyl-CoA deacylase {ECO:0000256|ARBA:ARBA00029672};
GN Name=LOC106153636 {ECO:0000313|RefSeq:XP_013383090.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013383090.1};
RN [1] {ECO:0000313|RefSeq:XP_013383090.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013383090.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + H2O = acetate + CoA + H(+); Xref=Rhea:RHEA:20289,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30089,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=3.1.2.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001831};
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
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DR RefSeq; XP_013383090.1; XM_013527636.2.
DR AlphaFoldDB; A0A1S3HAI9; -.
DR STRING; 7574.A0A1S3HAI9; -.
DR EnsemblMetazoa; g23933.t1; g23933.t1; g23933.
DR EnsemblMetazoa; XM_013527636.2; XP_013383090.1; LOC106153636.
DR GeneID; 106153636; -.
DR KEGG; lak:106153636; -.
DR InParanoid; A0A1S3HAI9; -.
DR OMA; FTDRTEI; -.
DR OrthoDB; 5486434at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0003986; F:acetyl-CoA hydrolase activity; IEA:UniProtKB-EC.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR21432:SF20; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR21432; ACETYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000085678}.
FT DOMAIN 49..220
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 314..468
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
SQ SEQUENCE 478 AA; 52142 MW; 759B5FA2E1AFE819 CRC64;
MASVLKNAVR LATKTLHESS KPGVKATSRF FHFYSPEPCH PIPDKLPKWM SAEEAVSVVR
SGMKVFVHGG AATPMPLVNA LAQHGLDSDL NGIEIMDMFL ICQTPYVQPE YKGIFRSNSF
FIGDNCREAV NDGRADFVPI FLSEIPLLFR RNLITLDVAL ISVSSPDEHG FCTLGPSVDC
ARAALQNARY IIALVNPNMP RTFGDGMVHM SHFDAMVQED YALPEYNSNR TTSEVEQQIG
RIIATNLVQD GATLQMGIGN IPDAVISALW SHRDLGIHSE MLGDSMIDLV ERGAITNAGK
NIHPGKIVGG FAVGTKRLYE YMHDNPMIVM LDIGFVNNTS IISQNPKVTA INSCIEIDLT
GQVCADSIGT WMYSGVGGQI DFLRGAALSM DGQGKPIIAL PSTTQKGESK IVPVLKAGAG
VTTSRAHAHY IVTEYGIASL FGKNLRQRAY ELIKIAHPDH RETLEKEAFA RLKCMPSP
//
