ID A0A1S3HIG1_LINUN Unreviewed; 562 AA.
AC A0A1S3HIG1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=sulfite oxidase {ECO:0000256|ARBA:ARBA00012505};
DE EC=1.8.3.1 {ECO:0000256|ARBA:ARBA00012505};
GN Name=LOC106155121 {ECO:0000313|RefSeq:XP_013385251.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013385251.1};
RN [1] {ECO:0000313|RefSeq:XP_013385251.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013385251.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=Mo-molybdopterin; Xref=ChEBI:CHEBI:71302;
CC Evidence={ECO:0000256|ARBA:ARBA00001924};
CC -!- PATHWAY: Energy metabolism; sulfur metabolism.
CC {ECO:0000256|ARBA:ARBA00004971}.
CC -!- PATHWAY: Sulfur metabolism. {ECO:0000256|ARBA:ARBA00004678}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_013385251.1; XM_013529797.1.
DR AlphaFoldDB; A0A1S3HIG1; -.
DR STRING; 7574.A0A1S3HIG1; -.
DR EnsemblMetazoa; g24878.t1; g24878.t1; g24878.
DR EnsemblMetazoa; XM_013529797.1; XP_013385251.1; LOC106155121.
DR GeneID; 106155121; -.
DR KEGG; lak:106155121; -.
DR InParanoid; A0A1S3HIG1; -.
DR OMA; VAQWARH; -.
DR OrthoDB; 1239at2759; -.
DR UniPathway; UPA00096; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0030151; F:molybdenum ion binding; IEA:InterPro.
DR GO; GO:0008482; F:sulfite oxidase activity; IEA:UniProtKB-EC.
DR GO; GO:0006790; P:sulfur compound metabolic process; IEA:UniProtKB-UniPathway.
DR CDD; cd02111; eukary_SO_Moco; 1.
DR Gene3D; 2.60.40.650; -; 1.
DR Gene3D; 3.10.120.10; Cytochrome b5-like heme/steroid binding domain; 1.
DR Gene3D; 3.90.420.10; Oxidoreductase, molybdopterin-binding domain; 1.
DR InterPro; IPR001199; Cyt_B5-like_heme/steroid-bd.
DR InterPro; IPR036400; Cyt_B5-like_heme/steroid_sf.
DR InterPro; IPR018506; Cyt_B5_heme-BS.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR005066; MoCF_OxRdtse_dimer.
DR InterPro; IPR008335; Mopterin_OxRdtase_euk.
DR InterPro; IPR000572; OxRdtase_Mopterin-bd_dom.
DR InterPro; IPR036374; OxRdtase_Mopterin-bd_sf.
DR PANTHER; PTHR19372:SF7; SULFITE OXIDASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR19372; SULFITE REDUCTASE; 1.
DR Pfam; PF00173; Cyt-b5; 1.
DR Pfam; PF03404; Mo-co_dimer; 1.
DR Pfam; PF00174; Oxidored_molyb; 1.
DR PRINTS; PR00407; EUMOPTERIN.
DR SMART; SM01117; Cyt-b5; 1.
DR SUPFAM; SSF55856; Cytochrome b5-like heme/steroid binding domain; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF56524; Oxidoreductase molybdopterin-binding domain; 1.
DR PROSITE; PS00191; CYTOCHROME_B5_1; 1.
DR PROSITE; PS50255; CYTOCHROME_B5_2; 1.
PE 4: Predicted;
KW Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Molybdenum {ECO:0000256|ARBA:ARBA00022505};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 57..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 98..176
FT /note="Cytochrome b5 heme-binding"
FT /evidence="ECO:0000259|PROSITE:PS50255"
SQ SEQUENCE 562 AA; 62159 MW; 32F8D88A903558FB CRC64;
MAAVLGKCAR LSAAVSRNVS PFSGLLGVQG ISARVSRLHT SPGKLTAKFQ KGRHQKVLLG
GVAAVAGVGV LVYFKKSRFW ILHAASGELQ GGDRKAGLPE YSLKDVEKHK GNGSRIWVTY
KHGVYDITEF IDLHPGGEKI KLAAGGSLEP FWHLYAAHKK PEVYEILETY RIGNFKDAGK
VALKDASDPY RFDPDRHPAL KRNTEKPFNA ESPPELLVDN FITPSSLFFV RNHLPVPEVD
MKKYRLVIEV QGKKPISLSL QDLKKKYKKH TITATLQCAG NRRKEMSSQR PVKGLSWTFT
AISNAEWSGV LLVDVLKAAG VSLDDPKNCH VQFEGLDKDE SNNPYGASVP IEIAMNPFRE
VLLAYEMNGE DIPTDHGYPV RVICPGIAGA RNVKWLSKIV VSPDESPSFW QQRDYKSFSP
SIDWDTADFS KSPALQDFPI TSAICVPSAG QKIDGEDGEI TLKGYAWSGG GRGIMRVDIS
ADGGKTWQVA SLQKPGQRPY QEWSWTLWEV DVPIPEGFKG NMELICKAVD SSHNVQPDSV
AGIWNLRGLM NNSWHRINVE VN
//
