ID A0A1S3HIM8_LINUN Unreviewed; 1307 AA.
AC A0A1S3HIM8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=MKL/myocardin-like protein 2 isoform X4 {ECO:0000313|RefSeq:XP_013385958.1};
GN Name=LOC106155604 {ECO:0000313|RefSeq:XP_013385958.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013385958.1};
RN [1] {ECO:0000313|RefSeq:XP_013385958.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013385958.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_013385958.1; XM_013530504.1.
DR EnsemblMetazoa; XM_013530504.1; XP_013385958.1; LOC106155604.
DR GeneID; 106155604; -.
DR OrthoDB; 2997330at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:UniProt.
DR Gene3D; 6.10.140.2040; -; 1.
DR Gene3D; 6.10.150.10; -; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR InterPro; IPR043451; Myocardin-like.
DR InterPro; IPR004018; RPEL_repeat.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR PANTHER; PTHR22793:SF12; MYOCARDIN-RELATED TRANSCRIPTION FACTOR, ISOFORM H; 1.
DR PANTHER; PTHR22793; MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED; 1.
DR Pfam; PF02755; RPEL; 1.
DR Pfam; PF02037; SAP; 1.
DR SMART; SM00707; RPEL; 3.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS51073; RPEL; 3.
DR PROSITE; PS50800; SAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT REPEAT 50..75
FT /note="RPEL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00401"
FT REPEAT 94..119
FT /note="RPEL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00401"
FT REPEAT 138..163
FT /note="RPEL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00401"
FT DOMAIN 542..576
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT REGION 1..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 69..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 191..237
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 268..305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 394..476
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 499..542
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 589..666
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 914..994
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 750..796
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 12..42
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..59
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 268..291
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 394..425
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 439..476
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 499..538
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 914..941
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 967..994
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1307 AA; 140643 MW; 9D1B2D7AC30DF3C5 CRC64;
MEHEQKEKER QQMQQNQQQT TQQQQQQSPT SPQNSLEEYS LQQSMDKNKE TLKRKLMLRR
PISELVEQGI YPSLKTPPAF AHQQKQLERA RTGDLIRHKI QNRPDRQSLV DHHILEDSKA
DPSLHEKQRQ LKRARVADEL NEKLSHRPGP LELVEDNILP AEGGFINKIK DGSISFHKTC
ESVGTDDSNL FVFGEDDNSN SEGVPSPSTA DDSDTNTQAS IGGSSSVPSP PELGSFMQKI
QNSSGSFTFN GPPITSESFV PINNTVTQAG VSSSSNSSSK SNYNSSGSSK NRKNKAKPKP
ATKSKVIKFH EYKGPPNASK VQQNQQNSSN AETPYHILLQ QQQLFLQWQL EFQQRNMMLM
PAKQAGGAAE GSPANQAATQ TGTVTLNNTP AAVTASGTTQ SVQQSQQQQQ QQQQQQQQQQ
QVASIQSPQP PPPSPQQQQQ QQQPQQQLQI QVHQPSPQQL PLQSPPQIHN QVALQQQQQQ
QQQQKQKQQQ QQIQQLKQQL HQQQHQSQKQ QSSQPIQQTK PQQASPHHST QQSSEQPKPK
TLEDLKVADL KAELKKRNLP VSGSKPHLIE RLKPYVDSIL SAWNENSTTG VQSAGTTLSA
STNSQQSKLP PKLVIKQEPQ TQPQPQKIPN SADEAGNVSM SSPPISPDQL SELNQSVATP
MSPDDLDMSI TSPTAFTWGI PMKKNSLTSA SQSSIPMAID ASRPPSVAPQ ESMDVDLNMS
FNGPPSIDSQ VSGYSSVSNT SNVSNLSSVT ATTEELVAKQ QKTIEELQRK LQESQLRLLQ
QQHEQQTLLV QQLQQQQSLL NATSSSGGSS AALTQTVAPP IVTQANTSQT QVVPSITISS
STSSPAVVAK PNVTFIQPQS LHDSLNMGQH KVLFATTGLN GQQLVFTSKP VDAMNINVVG
KLGTSAATTT VPVNGLSQNR ASSVPNSPTN SGFNKTPASK TLSGPFLIPL REPPKYDDAV
KNRQGSPINV DGGNSNSTAA SPAPTAVAAT KTQSQQMDDV LEILIRSGEL PPDAAQEPPP
TPKTQALGHS ISMPAISSFA QTGTVATAGS TVATTVPSSA IVVTAQTPAF MVAIPSTSIT
NNNNITTTTS SPAITSPTTV TIGGSPVKMV HSPGGNGSGK KAPPPLNITS ISSSPGPIPD
AINTGDLVSE FSDHFDLPSM DWDGADTDLV SLELPDGFRS LDPKTDQCDQ HGLLNVPSSA
ECGQGSGSSF HGSEPNLAAL GLNDNAEESM NMDVSDWLDV IMPNTGLTPL SATAPVAFPS
DPILTPKPQD VMELFNLDES DFQTPTGLES GMNWDRLVES ATSSGTH
//
