ID A0A1S3HJH4_LINUN Unreviewed; 634 AA.
AC A0A1S3HJH4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Aryl hydrocarbon receptor nuclear translocator homolog isoform X4 {ECO:0000313|RefSeq:XP_013385139.1};
GN Name=LOC106155060 {ECO:0000313|RefSeq:XP_013385139.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013385139.1};
RN [1] {ECO:0000313|RefSeq:XP_013385139.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013385139.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_013385139.1; XM_013529685.2.
DR AlphaFoldDB; A0A1S3HJH4; -.
DR EnsemblMetazoa; XM_013529685.2; XP_013385139.1; LOC106155060.
DR GeneID; 106155060; -.
DR OrthoDB; 2872674at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd18947; bHLH-PAS_ARNT; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR001067; Nuc_translocat.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR23042:SF76; ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR HOMOLOG; 1.
DR PANTHER; PTHR23042; CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS; 1.
DR Pfam; PF00010; HLH; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF14598; PAS_11; 1.
DR PRINTS; PR00785; NCTRNSLOCATR.
DR SMART; SM00353; HLH; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50888; BHLH; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Receptor {ECO:0000313|RefSeq:XP_013385139.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 48..101
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT DOMAIN 120..191
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 327..376
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 425..467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 494..634
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..44
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 425..451
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 494..519
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 529..606
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 634 AA; 69326 MW; 09DF96DB339259B9 CRC64;
MSMAAASAAP PGALDGGKKR KRASGGGSDD EDSQGFSRDQ DTVDKERFAR ESHCEIERRR
RSKMATYVNE LCDMVPACST LARKPDKLTI LRLAAAHMKT LRGTGNTSSD GSYKPSFLTD
QELKHLILEA ADGFLFVAQC DTGRVIYVSD SVTPVLNQSQ SDWYTSTLYD LVHPDDVEKV
REQLSTTESQ NTGRILDLKT GTVKKEGHQS SMRLCMGSRR GFICRMRLGA IQVDTMTTSH
AIRLRQRNSL GPSGDGHQYA VVHITGYIKN WPPAGVQIER TETDEPHSGS HCCLVAIGRL
QVTGTPNCSD LIGPNATSEF ISRHSIDGKF TFADQRVANL LGYQPVDLLG KSAYDFYHPE
DKGHMKDSFE QVLKLKGQVM SIMYRFRAKN GEWVWLRTSS FSFQNPYTDE VEYIVCTNSL
AKSSQQQSAG QVSPGDQSTD PTPTINTFAS PHRGMGASEG ISSMAQNAGD SRYTGEVYPG
MVPGSYSYNR SPVKSYSNIP QSSTQIPSTS QQGSWPSQVL YRRGGSEYSG SAGYSQMSPS
TSPGGPSYTQ LSSGQRPATS QDPSYQGSGS STALWQHWQA GSEAGAQQTA TQSAQAQQQQ
PQQQPEELGE VFRMLEPTNP EFGDLSGMFS TFTE
//
