ID A0A1S3HKR8_LINUN Unreviewed; 701 AA.
AC A0A1S3HKR8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Stromal interaction molecule homolog {ECO:0000313|RefSeq:XP_013386698.1};
GN Name=LOC106156136 {ECO:0000313|RefSeq:XP_013386698.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013386698.1};
RN [1] {ECO:0000313|RefSeq:XP_013386698.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013386698.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR RefSeq; XP_013386698.1; XM_013531244.1.
DR AlphaFoldDB; A0A1S3HKR8; -.
DR STRING; 7574.A0A1S3HKR8; -.
DR EnsemblMetazoa; XM_013531244.1; XP_013386698.1; LOC106156136.
DR GeneID; 106156136; -.
DR KEGG; lak:106156136; -.
DR InParanoid; A0A1S3HKR8; -.
DR OrthoDB; 54068at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005246; F:calcium channel regulator activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW.
DR GO; GO:0051049; P:regulation of transport; IEA:UniProt.
DR CDD; cd09504; SAM_STIM-1_2-like; 1.
DR CDD; cd11722; SOAR; 1.
DR Gene3D; 1.10.238.180; -; 1.
DR Gene3D; 1.10.287.3550; -; 1.
DR Gene3D; 1.20.5.340; -; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR032393; SOAR.
DR InterPro; IPR037608; STIM.
DR PANTHER; PTHR15136; STROMAL INTERACTION MOLECULE HOMOLOG; 1.
DR PANTHER; PTHR15136:SF5; STROMAL INTERACTION MOLECULE HOMOLOG; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF16533; SOAR; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Calcium transport {ECO:0000256|ARBA:ARBA00022568};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..701
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010175278"
FT TRANSMEM 203..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 122..180
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 545..701
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 230..330
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 558..607
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 614..636
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 645..662
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 663..683
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 701 AA; 78953 MW; 6F92978DC25BD12D CRC64;
MIKRSTTTAV TVTLLCVLCV GESQQQAPVT TLKQKAQDFS CPSEDKECNK DKLGFDAISL
LHGKLDDDKN GNVDLSESDE FLRDELQYTD GFERHNIFHG NDKQITVDEL WVQWKQSEVY
NWTVDDVLDW VTVSVDLPQY AENFRVNAVD GTVLPRIAAN SNHFLSGILG IKNPVHKQKL
SLKAMDVVLF GPPKKGHSYI KDIALVASLV IAIGGCWFAY IQHKYSQSHM KKMITDLDNL
QRAEDALTEL QEKLHRAQKS QQEVVQEKQH LEAKMKDEIQ DAKLEAERLK LAREGTEADM
TRLKLAEEEL AQVRSALRQA ERELENMNWR PPADLQDWLQ LTYEIELTHY NTKKLSAERQ
LAAAKDACER IRKKRSAFMG SLRLAHSSSI DDVDRRIIDA RSSLEEVGRD LQERLQRWRQ
IEELTGFAIL TNPGMAQLSS KLYGSSHPQG HDTAAYLRPT DIDDGSDEDI PPGYHAAVAH
LAAANQYLRH SCSFPGQLSK VVTELAAKEA KLRQQGARPG EIYALRWRAR TRIAHLQALS
HASLNGEQRR ISRQHAHAQE DTSSSSDVSP TGQVVFGIEE SCQNDQSSDK SSTSSQLSTY
KQSKSLDRDT MSVSRKPLVN SCSEGSLSTL SEATTEGRKR LGTFPKHSIQ SSVPSTVAEE
HSSPEEGSTE HLDHSDRKEK KKRKLLPNFL KKDHSDKWKT S
//
