ID   A0A1S3HWI7_LINUN        Unreviewed;       436 AA.
AC   A0A1S3HWI7;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Saccharopine dehydrogenase-like oxidoreductase {ECO:0000313|RefSeq:XP_013390407.1};
GN   Name=LOC106158846 {ECO:0000313|RefSeq:XP_013390407.1};
OS   Lingula unguis.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC   Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX   NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013390407.1};
RN   [1] {ECO:0000313|RefSeq:XP_013390407.1}
RP   IDENTIFICATION.
RC   TISSUE=Gonads {ECO:0000313|RefSeq:XP_013390407.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the saccharopine dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00038048}.
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DR   RefSeq; XP_013390407.1; XM_013534953.2.
DR   AlphaFoldDB; A0A1S3HWI7; -.
DR   STRING; 7574.A0A1S3HWI7; -.
DR   EnsemblMetazoa; XM_013534953.2; XP_013390407.1; LOC106158846.
DR   GeneID; 106158846; -.
DR   KEGG; lak:106158846; -.
DR   InParanoid; A0A1S3HWI7; -.
DR   OrthoDB; 5479972at2759; -.
DR   Proteomes; UP000085678; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR005097; Sacchrp_dh_NADP.
DR   PANTHER; PTHR12286:SF5; SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE; 1.
DR   PANTHER; PTHR12286; UNCHARACTERIZED; 1.
DR   Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        288..307
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          18..151
FT                   /note="Saccharopine dehydrogenase NADP binding"
FT                   /evidence="ECO:0000259|Pfam:PF03435"
SQ   SEQUENCE   436 AA;  47591 MW;  DDF4E28DEDE49980 CRC64;
     MEGVRGAREY SAREYDFIVF GASGFTGQFV VSQLAKLRDE EPALKWAVGG RSMSKLVNTL
     KEAGSRAGTS LASIDCLLAD SKDPDSLIEL CGKGRVVLSC VGPYRFCGEP VVKACVEAGT
     NYVDICGEPQ FLEEMQLRYD AQAKEKGIYI VGSCGFDSIP AEMGLLFTKN KFEGDLNSVE
     SFIQIKFAVP EVKGAKINFA TWQSAVHGFA HEGELKPLRK LLCPEPLPKP IHRVKNRGVL
     FYSKEVGSWC IPFLGSDRSI VYRSQVISYR DRKERPIQFL PYTKLPSLMS ALAVLSFGIV
     FGILAKFKCG RWLLEKFPGI FSGGLVSKQG PPLAQIQGSS FTMTFFGKGY SQILPDADQQ
     HNEAPDKTIV TSVTGPEAGY VTTPICMVDA ALVILREQNM LPAGGGVIPP GAAFAKTSLI
     EKLQKHGMKF EVQPST
//