ID A0A1S3HY02_LINUN Unreviewed; 427 AA.
AC A0A1S3HY02;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Rho guanine nucleotide exchange factor 38-like isoform X2 {ECO:0000313|RefSeq:XP_013390441.1};
GN Name=LOC106158873 {ECO:0000313|RefSeq:XP_013390441.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013390441.1};
RN [1] {ECO:0000313|RefSeq:XP_013390441.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013390441.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_013390441.1; XM_013534987.1.
DR AlphaFoldDB; A0A1S3HY02; -.
DR EnsemblMetazoa; XM_013534987.1; XP_013390441.1; LOC106158873.
DR GeneID; 106158873; -.
DR KEGG; lak:106158873; -.
DR OrthoDB; 9305at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR PANTHER; PTHR46006:SF5; DH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46006; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000085678}.
FT DOMAIN 39..230
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
SQ SEQUENCE 427 AA; 49142 MW; DB52081930BD92D8 CRC64;
MKKKSKGPVC EDCNKTISVL DLEDCVETLC TKCHSRRVER KETIQELVDT ELSYGRDLRI
IKEEFMAPME TASLLTPEQL DTIFINLQEL IDINDKFADK LQDLVELANE QGDEDYVTVY
IGQLFLESSN MFLAFENYCV KQAAAPLLLE QLEKEKELLR IFLHVSQTEN SLLRRMNLKS
FLMVPVQRIM KYPLLLGRLH KSTSSHHEDR EAIKEAQCRV EEILDHINAK TKASATGLRL
RRKGSGSKKS IGTDNIELNK VALETLCWTR NEVKIITAGK LQYAQPADST WPRKYKNLKF
APIFGVLATL GNPKPYNTLD EVMLFPRPHT VPQQAALVII REKGGRFQSI REPMYLDKCV
VAIDPELPEV FEIHEMAKDV FLFKAEDPKD TLLWYRHLKY LSLGQGTWRH RRNGLANIMI
KNKPKPV
//
