ID A0A1S3I0F1_LINUN Unreviewed; 254 AA.
AC A0A1S3I0F1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Tyrosine kinase receptor Cad96Ca-like {ECO:0000313|RefSeq:XP_013391738.1};
GN Name=LOC106159856 {ECO:0000313|RefSeq:XP_013391738.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013391738.1};
RN [1] {ECO:0000313|RefSeq:XP_013391738.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013391738.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-
CC [protein]; Xref=Rhea:RHEA:10596, Rhea:RHEA-COMP:10136, Rhea:RHEA-
CC COMP:10137, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:46858,
CC ChEBI:CHEBI:82620, ChEBI:CHEBI:456216; EC=2.7.10.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001171};
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DR RefSeq; XP_013391738.1; XM_013536284.1.
DR AlphaFoldDB; A0A1S3I0F1; -.
DR STRING; 7574.A0A1S3I0F1; -.
DR EnsemblMetazoa; XM_013536284.1; XP_013391738.1; LOC106159856.
DR GeneID; 106159856; -.
DR KEGG; lak:106159856; -.
DR InParanoid; A0A1S3I0F1; -.
DR OrthoDB; 5390692at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00192; PTKc; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008266; Tyr_kinase_AS.
DR InterPro; IPR020635; Tyr_kinase_cat_dom.
DR PANTHER; PTHR24416:SF485; PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET; 1.
DR PANTHER; PTHR24416; TYROSINE-PROTEIN KINASE RECEPTOR; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR PRINTS; PR00109; TYRKINASE.
DR SMART; SM00219; TyrKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Kinase {ECO:0000313|RefSeq:XP_013391738.1};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Receptor {ECO:0000313|RefSeq:XP_013391738.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW Transferase {ECO:0000313|RefSeq:XP_013391738.1}.
FT DOMAIN 1..225
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 55
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 254 AA; 28954 MW; 9E7460CB7720BF60 CRC64;
MDAPVYAIVK EKNVEVLRQN IKILEKIGSG AYGQVYKGSV LQLNRNQGWT TVAIKTIKDV
ENAAEAKGLL DELKVMLELS PHPNVILHRD LAARNILVAE DKTCKISDFG FAKDVIESHQ
YERKTQGRLP VRWMSPEALY DNRYSTQSDV WAYGVLVWEI VTLGSSPYPG MSAKQVMEAV
TEGYRMPQPP HCSQDMYNIM LSCWEDNPSS RPLFKAITVS LNDLLSRDYE VLTLGKFEEK
LYEDIDQFRL DEKC
//
