ID A0A1S3I242_LINUN Unreviewed; 786 AA.
AC A0A1S3I242;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Myotubularin-related protein 10-B isoform X1 {ECO:0000313|RefSeq:XP_013392335.1};
GN Name=LOC106160294 {ECO:0000313|RefSeq:XP_013392335.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013392335.1};
RN [1] {ECO:0000313|RefSeq:XP_013392335.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013392335.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non-
CC receptor class myotubularin subfamily. {ECO:0000256|ARBA:ARBA00007471}.
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DR RefSeq; XP_013392335.1; XM_013536881.1.
DR AlphaFoldDB; A0A1S3I242; -.
DR STRING; 7574.A0A1S3I242; -.
DR EnsemblMetazoa; g69.t1; g69.t1; g69.
DR EnsemblMetazoa; XM_013536881.1; XP_013392335.1; LOC106160294.
DR GeneID; 106160294; -.
DR KEGG; lak:106160294; -.
DR InParanoid; A0A1S3I242; -.
DR OMA; APHQLYD; -.
DR OrthoDB; 5474662at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR CDD; cd14537; PTP-MTMR10-like; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR022587; MTMR12-like_C.
DR InterPro; IPR010569; Myotubularin-like_Pase_dom.
DR InterPro; IPR030564; Myotubularin_fam.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR PANTHER; PTHR10807:SF110; FI17948P1; 1.
DR PANTHER; PTHR10807; MYOTUBULARIN-RELATED; 1.
DR Pfam; PF12578; 3-PAP; 1.
DR Pfam; PF06602; Myotub-related; 2.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS51339; PPASE_MYOTUBULARIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000085678}.
FT DOMAIN 212..646
FT /note="Myotubularin phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51339"
FT REGION 763..786
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 769..786
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 786 AA; 89241 MW; 8BCECB3C6D887637 CRC64;
MSKGFKIHVD IFGQEEQTQS EIDKNAVAVF QATLEPQLLP GELIVGHAQN VLKFSAYSEQ
KQGISGSLFC TNFKVSFVTA DRSSYDGEHN NQRNLLLGEN DIALCNIDDI YQASYPKLPT
ETFVPKIVST GKRKKFTPGG NLTGKVKTLE IRCKDLSIHT FSFKFSPKDE AKSTVTAILH
HAFPTRLELM FAFEYQDPNR QPGKQTHHTT MFTIKSDWSK ELDRLHCADA WRVTQVNEHF
NMTDSMPECF VVSSKLYDND LLKAAPHFLD SRVPAWCYSY KNGTALVRMA CLRSESALSQ
TENKGIIVVS EIESMLEAVR LVHPNKRQAE IADLNKQCPS VKDIANSFMK LKEICMPVSL
KEFWVEDLNW FARLSDTGWL QNVTRCLETA VEIVIKMAGD TPVSVVMKES DSKDLCCVIS
SLVQLMLDPC FRTQRGFQNL VQREWVVMGH PFLDRHGHIK KNEEDVSPVF LMFLDCVWQM
LQQFPSAFAF SETYLTTLWD STFIGLFETF LFNSQHQRMM CSKEGIPYGP KKGAQLLSVW
DWSLQFKNEE QSLFKNPLYV AEHEVVKHRR ESASLEDSKR SLAEEKGASA LESSTEVNKD
SSLVRNLGYL IVDDYNDTLQ TISKSDLDIL LPQVKGPLIK LWSQCFLRWL IPVQIIGGGS
PSEYFQQCIL VEEILHLKHR VKVLESSQQD IPNDRVRRPK SDLFFSQDIH GVPHKLKADV
LTSSFPYLPL GPLNRRNILG TPLSKYFEES MVAYGLGVSE NGAAAELEDT DDSEGRNSKS
RGENLE
//
