ID A0A1S3I506_LINUN Unreviewed; 1132 AA.
AC A0A1S3I506;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Uncharacterized protein LOC106160403 {ECO:0000313|RefSeq:XP_013392449.1};
GN Name=LOC106160403 {ECO:0000313|RefSeq:XP_013392449.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013392449.1};
RN [1] {ECO:0000313|RefSeq:XP_013392449.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013392449.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_013392449.1; XM_013536995.1.
DR AlphaFoldDB; A0A1S3I506; -.
DR STRING; 7574.A0A1S3I506; -.
DR EnsemblMetazoa; XM_013536995.1; XP_013392449.1; LOC106160403.
DR GeneID; 106160403; -.
DR KEGG; lak:106160403; -.
DR InParanoid; A0A1S3I506; -.
DR OrthoDB; 721380at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0005829; C:cytosol; IEA:UniProt.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR GO; GO:0050832; P:defense response to fungus; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.25.40.370; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039203; RGA2/3-like.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR36766; PLANT BROAD-SPECTRUM MILDEW RESISTANCE PROTEIN RPW8; 1.
DR PANTHER; PTHR36766:SF3; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13676; TIR_2; 1.
DR Pfam; PF00400; WD40; 4.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50104; TIR; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 4: Predicted;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 72..205
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REPEAT 874..908
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 917..958
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1046..1089
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 623..664
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 624..649
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1132 AA; 126737 MW; 2E617076D3230D7F CRC64;
MAKYDDDVIG NFHLILRFAK STRSTHRIAV IEQATGTTCI TRLASGRQLL NKGTGTRIIF
THSYDDMPQK VFLVGIELNP RAKHWRAALV DSLKTQSNEE FHFLDETNIP PGAIIIDELI
DFIRNCDKTV LVITSDFLSD PSCLYAANLA LSLENDTERP RRGSVVVVLL QDTIVPYKYT
HKRDVIHHDD PEFLKKLSKQ LSKELEWGTK PLVHGIQVHN PHNLLGRTDD VVFIAESFMG
QVPEEGSNMF GISGAPGIGK TSLATLICRY IYRRMFLHIY WIHCGKAPDV VKIISSVRRH
LQGSESQEDF ADRISARSWL IQFTMHEKIL FVLDDVWNPD DASVFTAISK DCLLLITTRD
RAVINMLNVR IYTLDHLDVE NAWQLFLKCA NVTEKLLNDH KITKEANAIH SYLGGYPLAI
ALVASSLRQG ATSVSQPFSS QRWRDMAASL KEKDKLWMES RRLPIDSYPE TFVGAFEATF
ACLRDAGDTN KPYSMLQEIL LKVSLFKKDA LIQSSTLAIL CSYMQDKSNA EKQDKVARHV
RECLFTLADK SLLRFKLEDE DGDCYFRIHD LVLQYIQNKT ETLWGPDGIR RMHTALLAAY
VAAAEGTAGL QHIEKLQLEE PAAGCSAEKD RSDSGFQDDL ERSAERHSPS KGRPMISGSN
TNSSKDQLGC SSCYENDQAI VLSYPWWNLD FSGDKYVYTN FIHHCTAMGK EFKSLYRGLL
CSFRWLQAKL NKTSLSEIIS DFELFECDCQ FSHLHGAINK ALLLHAPAII RDKKQLGPVF
LGSLSNLEIV GISDFLKAVR SQLFEDADSC FLPDRACISP PNGHVVKTYS AHNGTAVLGL
GVLKDSTIVT TSGDGFVRLI DPITGGETCL GSDLTKHNDL VTCFGVNSSE TLVVTAACDS
VVKLWDLKGK CLRETFSNIH NRQIFSLVLS ADGESGLTVS GDKTIKLWYL NDGSVQFTYA
ALTDVVACAC FTNLSEKEIF FASCSYDESV CLWRKNSPEC PVTSCNPKLG VLYTLFFSRY
QRQLYVGGKT GIGVLNFPSL EVRRILKGHE GGTFALCLAR YESHSLLLSG GADGRVKFWD
LNDDHSLVFQ VQIHSAAVRG IQCAFQEKKD DYLHGIGRPI SKTVVLFSFQ FR
//
