ID A0A1S3IB87_LINUN Unreviewed; 550 AA.
AC A0A1S3IB87;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Solute carrier family 41 member 1 {ECO:0000313|RefSeq:XP_013395116.1};
GN Name=LOC106162380 {ECO:0000313|RefSeq:XP_013395116.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013395116.1};
RN [1] {ECO:0000313|RefSeq:XP_013395116.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=26383154;
RA Luo Y.J., Takeuchi T., Koyanagi R., Yamada L., Kanda M., Khalturina M.,
RA Fujie M., Yamasaki S.I., Endo K., Satoh N.;
RT "The Lingula genome provides insights into brachiopod evolution and the
RT origin of phosphate biomineralization.";
RL Nat. Commun. 6:8301-8301(2015).
RN [2] {ECO:0000313|RefSeq:XP_013395116.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC41A transporter family.
CC {ECO:0000256|ARBA:ARBA00009749}.
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DR RefSeq; XP_013395116.1; XM_013539662.1.
DR AlphaFoldDB; A0A1S3IB87; -.
DR EnsemblMetazoa; XM_013539662.1; XP_013395116.1; LOC106162380.
DR GeneID; 106162380; -.
DR KEGG; lak:106162380; -.
DR InParanoid; A0A1S3IB87; -.
DR OrthoDB; 5124745at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.10.357.20; SLC41 divalent cation transporters, integral membrane domain; 2.
DR InterPro; IPR006667; SLC41_membr_dom.
DR InterPro; IPR036739; SLC41_membr_dom_sf.
DR InterPro; IPR045349; SLC41A1-3.
DR PANTHER; PTHR16228; DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41; 1.
DR PANTHER; PTHR16228:SF7; SOLUTE CARRIER FAMILY 41 MEMBER 1-LIKE PROTEIN; 1.
DR Pfam; PF01769; MgtE; 2.
DR SUPFAM; SSF161093; MgtE membrane domain-like; 2.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 129..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 219..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 353..375
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 446..467
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 479..503
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 515..541
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 173..306
FT /note="SLC41A/MgtE integral membrane"
FT /evidence="ECO:0000259|Pfam:PF01769"
FT DOMAIN 385..533
FT /note="SLC41A/MgtE integral membrane"
FT /evidence="ECO:0000259|Pfam:PF01769"
FT REGION 1..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 70..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..51
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 550 AA; 59046 MW; 92F363B15BBCDB4C CRC64;
MLHVRKKMVP HILPNCSTTI PNKSGDDSGR ELTSPRHRRG SGEPGDKYVH QKHNGSHAIL
DNTIETLRTA SGNSLSNGSA PLEEEEIVSD TEPLLQQQHR EASRKLEGDF DDGPEFDFRS
PPPETEETAL TIALQVFVPY LIAGFGTVGA GLVLDVVQHW EVFAKVSEVF ILVPALLGLK
GNLEMTLASR LSTQANLGNM DKASEQWKMI GGNLALTQAQ AIIVGFLAAI AAMVMGWIPE
GKFSLSHALL LSASSALTAS LASLVLGIVM IGVVMLSRKC GINPDNVATP IAASLGDLTT
LTFLASISMV LFKAIGQQVW LSPLVVSLCL VVTPVWLVVA YRNKYTHEVV YTGWTPIICA
MVISSVGGLV LDFAVSNFHG IAVFQPVING VGGNLVAVQA SRLSTALHKV SVPGRLPEGS
PRGCANPFSV FFGKVRGLRG MSPKTVRVLI LMVIPGHLIF IYTIAFMSAG HTSITWRFAL
VYLSAAIIQV AILLYIAIWM VHYMWKNGDD PDNFAIPYLT ALGDLLGTGL LAVAFLILYS
VGDKDADVGD
//
