ID A0A1S3IBH1_LINUN Unreviewed; 356 AA.
AC A0A1S3IBH1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500};
GN Name=LOC106162451 {ECO:0000313|RefSeq:XP_013395206.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013395206.1};
RN [1] {ECO:0000313|RefSeq:XP_013395206.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013395206.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Ligand for members of the frizzled family of seven
CC transmembrane receptors. {ECO:0000256|RuleBase:RU003500}.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|RuleBase:RU003500}.
CC -!- SIMILARITY: Belongs to the Wnt family. {ECO:0000256|ARBA:ARBA00005683,
CC ECO:0000256|RuleBase:RU003500}.
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DR RefSeq; XP_013395206.1; XM_013539752.2.
DR AlphaFoldDB; A0A1S3IBH1; -.
DR STRING; 7574.A0A1S3IBH1; -.
DR EnsemblMetazoa; XM_013539752.2; XP_013395206.1; LOC106162451.
DR GeneID; 106162451; -.
DR KEGG; lak:106162451; -.
DR InParanoid; A0A1S3IBH1; -.
DR OrthoDB; 2874082at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd19344; Wnt_Wnt16; 1.
DR Gene3D; 3.30.2460.20; -; 1.
DR InterPro; IPR005817; Wnt.
DR InterPro; IPR043158; Wnt_C.
DR InterPro; IPR018161; Wnt_CS.
DR PANTHER; PTHR12027:SF70; PROTEIN WNT-16; 1.
DR PANTHER; PTHR12027; WNT RELATED; 1.
DR Pfam; PF00110; wnt; 1.
DR PRINTS; PR01349; WNTPROTEIN.
DR SMART; SM00097; WNT1; 1.
DR PROSITE; PS00246; WNT1; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473,
KW ECO:0000256|RuleBase:RU003500};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687,
KW ECO:0000256|RuleBase:RU003500}.
SQ SEQUENCE 356 AA; 40172 MW; 22E3F1EC802F689D CRC64;
MAQSRWGEVV LILGLYLCGT HGLAKWMYLG VSSIATSHDK IENKNTCKGL PLDTQQVQVC
KKHPDSILCI STGARQGIYE CQYQFQHERW NCTTTKNQTV FGTLLDKGTK ETAFIYAILS
AGVVHAVTQA CSAGNLTECS CDLRLQGQKT EDGWTWGGCS DNVDYGVWFG KTFVDAPDTS
SHKSGRNVRM LMNLHNNEVG RKAIVKQMRR QCRCHGVSGS CAVKTCWKGL PPFRQIGNYL
KTKYEHSVQV APRSKRKLRR RERVKRKVPI PVDILVHLHR SPNFCRADAK QGIPGTRGRM
CNKNSRSQDS CDLLCCGRGY NTQVKRHSER CHCKFVWCCY VKCQTCVSQV DIHTCK
//
