ID A0A1S3IC53_LINUN Unreviewed; 726 AA.
AC A0A1S3IC53;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Nucleoporin NUP42 {ECO:0000256|ARBA:ARBA00039886};
DE AltName: Full=Nucleoporin-like protein 2 {ECO:0000256|ARBA:ARBA00042384};
GN Name=LOC106162896 {ECO:0000313|RefSeq:XP_013395822.1,
GN ECO:0000313|RefSeq:XP_013395902.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013395822.1};
RN [1] {ECO:0000313|RefSeq:XP_013395822.1, ECO:0000313|RefSeq:XP_013395902.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013395822.1,
RC ECO:0000313|RefSeq:XP_013395902.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Required for the export of mRNAs containing poly(A) tails
CC from the nucleus into the cytoplasm. {ECO:0000256|ARBA:ARBA00037262}.
CC -!- SUBCELLULAR LOCATION: Nucleus membrane {ECO:0000256|ARBA:ARBA00004335};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004335};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004335}.
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DR RefSeq; XP_013395822.1; XM_013540368.1.
DR RefSeq; XP_013395902.1; XM_013540448.1.
DR STRING; 7574.A0A1S3IC53; -.
DR EnsemblMetazoa; XM_013540368.1; XP_013395822.1; LOC106162896.
DR EnsemblMetazoa; XM_013540448.1; XP_013395902.1; LOC106162896.
DR GeneID; 106162896; -.
DR KEGG; lak:106162896; -.
DR OrthoDB; 325136at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 4.10.1000.10; Zinc finger, CCCH-type; 1.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR InterPro; IPR008913; Znf_CHY.
DR InterPro; IPR037274; Znf_CHY_sf.
DR PANTHER; PTHR46527:SF1; NUCLEOPORIN NUP42; 1.
DR PANTHER; PTHR46527; NUCLEOPORIN-LIKE PROTEIN 2; 1.
DR Pfam; PF00642; zf-CCCH; 1.
DR Pfam; PF05495; zf-CHY; 1.
DR SMART; SM00356; ZnF_C3H1; 2.
DR SUPFAM; SSF90229; CCCH zinc finger; 2.
DR SUPFAM; SSF161219; CHY zinc finger-like; 1.
DR PROSITE; PS50103; ZF_C3H1; 2.
DR PROSITE; PS51266; ZF_CHY; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00723}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00601}.
FT DOMAIN 26..54
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 123..151
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 599..668
FT /note="CHY-type"
FT /evidence="ECO:0000259|PROSITE:PS51266"
FT ZN_FING 26..54
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT ZN_FING 123..151
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 53..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 368..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 694..726
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 376..423
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 726 AA; 82166 MW; E385C07CF59A1087 CRC64;
MSTRQELVQK QEKSGIVSVM SQASDPSPIS ICQFYANKRW CKFGKRCKFQ HTRGSQPFSD
EEDPTGAKCS DSKVDSQSLK EVAIDNATEG TDQSELETAQ VVEVSSETEK PHKLKPKVTK
ENAEGHKICK FFARTGRCRF GSRCYFFHER SSGEQERKGV MKENVESADA DIKEEACVNV
QSRNPPRKES FRPPYRPSRP KLVFLMSELS LEKIEELRNS EILYLKKRFP RVSRSQVELT
EGETVDEYRI EFTASDPDWP FDVKSLELTV SFPLKYPQVP FNIKFPEDQT LPDTVRSYVS
YNVKGWIEET WKELQQAGKA ELLLRRFLKW LDKKMEEFFT EGLKQLKRQL AAKAAGLEFI
PFFQLQGSQS QDIHTSREPE PGEEEPSHMS PEHEVSEQEV DSGDGNVDKE NKDIGAESEK
GNLDPVKKGT EIRLLKLQLL EDAATLLGTK IKIIIQCSRC KNLAEIVTPQ NQLNAVPCPK
CASCQYVTFR PSLAHQMSSV IGYLDLQGCV AFDLVLADCV FSVGCMNCSK EMKLEGLAPG
QMSDTRCLGC YSKLKVAVEA VKFQQLHPAN ITDTHGANVI VVKKAPRAVK DPAIQEGKPL
PETGTCKHYR KSFRWLRFPC CGKCYPCDVC HDDKEGDHEM KFANRMVCGF CAKEQPYSNE
RPCISCHSHL KKVSTKHWEG GKGCRDKIAM SRDDKKKYAN SSKTISKKQQ ALDKPGNAKT
TKLRHT
//
